Publications by authors named "Chung-Kuang Chin"
A lobule-mimetic cell-patterning technique for on-chip reconstruction of centimetre-scale liver tissue of heterogeneous hepatic and endothelial cells via an enhanced field-induced dielectrophoresis (DEP) trap is demonstrated and reported. By mimicking the basic morphology of liver tissue, the classic hepatic lobule, the lobule-mimetic-stellate-electrodes array was designed for cell patterning. Through DEP manipulation, well-defined and enhanced spatial electric field gradients were created for in-parallel manipulation of massive individual cells.
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- * Researchers tested different conductivity levels of media to see how they affect cell adhesion and viability, comparing traditional DEP buffer with new formulations M1, M2, and M3.
- * A prototype microchip with precisely arranged titanium electrode arrays was designed to improve cell patterning, optimizing factors like electrode dimension and voltage signal frequency.