A disposable breath sensing tube with on-tube single-nanowire sensor array for on-site detection of exhaled breath biomarkers.

This paper presents a novel disposable breath-sensing tube with an on-tube single-nanowire (NW) sensor array for noninvasive, simple, and on-site detection of exhaled breath biomarkers. Although various noninvasive detection methods for lung cancer biomarkers in breath samples exist, they are unsuitable for self-diagnostics and immediate detection because they entail complicated handling procedures and are time intensive. In this study, we simulated, fabricated, and characterized disposable nanosensors by using single TiO and Ag NWs in flexible plastic tubes.

Essential functions of C terminus of Drosophila Topoisomerase IIIα in double holliday junction dissolution.

Topoisomerase IIIα (Top3α) is an essential component of the double Holliday junction (dHJ) dissolvasome complex in metazoans, along with Blm and Rmi1/2. This important anti-recombinogenic function cannot be performed by Top3β, the other type IA topoisomerase present in metazoans. The two share a catalytic core but diverge in their tail regions.