Publications by authors named "Chung Ma Lin"
Ann Rheum Dis
August 2022
Article Synopsis
- An interferon gene signature (IGS) is found in about 50% of early rheumatoid arthritis patients and negatively impacts their initial treatment response.
- A multicenter study with 191 patients confirmed that a higher baseline IGS correlates with increased levels of circulating IFN-α and worse clinical outcomes after six months.
- The findings suggest that IFN-α triggers harmful immune responses in patients, highlighting the IGS as a potential biomarker for predicting disease severity and the need for targeted therapies.
