Death Preparation and Quality of Life amongst Family Caregivers of Terminal Cancer Patients: A Multicentre Cross-sectional Study.

Objectives: Caring for ill cancer patients imposes a considerable burden on families, significantly reducing quality of life (QoL). This study examined the association between death preparation and QoL amongst family caregivers (FCs) of terminally ill patients with cancer in South Korea.

Materials And Methods: A multicentre cross-sectional survey using questionnaires was conducted in nine inpatient palliative care units in South Korea.

Centimeter-Scale Ultrathin Platinum Monosulfide Films with Large Negative Temperature Coefficient of Resistance for Deformable Visible-to-Mid-Infrared Photodetectors.

Broadband photodetectors covering a spectrum range of visible-to-mid-infrared (Mid-IR) are widely utilized for a range of applications, such as chemical sensing and medical devices. As their physical form factors evolve, a variety of photoresponsive electronic materials have been explored to adapt their demanded mechanical deformability. Herein, we report on a chemical vapor deposition (CVD) growth of centimeter-sized ultrathin (i.

Temporal distribution shifts of Chum salmon (Oncorhynchus keta) with sea surface temperature changes at their southern limit in the North Pacific.

Understanding the responses of marine organisms to environmental changes at their distribution limits is crucial for predicting climate-change associated habitat changes. This study analyzed the effect of sea surface temperature (SST) on the temporal distribution of Chum salmon (Oncorhynchus keta) in the eastern and southern coastal waters of Korea (ESCK) and on the southern limit of their distribution in the North Pacific. The temporal distribution of Chum in the ESCK and adjacent rivers was statistically compared based on three SST types (T1-T3).

Enhancement within the orbits and superficial temporal artery: MRI clues to the diagnosis of giant cell arteritis.

Purpose: Giant cell arteritis can have protean manifestations, many of them non-specific. We describe a patient whose initial presentation was most consistent with brainstem stroke, but who was ultimately diagnosed with and treated for giant cell arteritis.

Observations: A 76-year-old woman presented with abrupt onset diplopia, headache, nausea and vomiting.

Patient Acceptance of Death and Symptom Control/Quality of Care Among Terminal Cancer Patients Under Inpatient Hospice Care: A Multicenter Cross-Sectional Study.

Introduction: Patient attitude to death is associated with outcomes in hospice care settings. This Korean study investigated the association between terminal cancer patient death acceptance and symptom control and quality of care (QoC) as perceived by family caregivers (FCs).

Methods: A multicenter cross-sectional survey was conducted in nine inpatient hospice care units, and the data of 108 dyads (terminal cancer patients who responded to the revised Death Attitude Profile and their primary FCs) were analyzed.

Urolithin A attenuates apoptosis and ferroptosis in hyperlipidemic tenocytes through PPARδ/ALDH2-mediated antioxidative signaling.

Urolithin A (URA), a product of the gut microflora from foods rich in ellagitannins found in berries and nuts, has demonstrated anti-inflammatory and antioxidative stress properties in various disease models. Ferroptosis, an iron-dependent form of cell death, is considered a pathogenic cause of tendinopathy. However, the effects of URA on hyperlipidemic tenocytes and the related molecular mechanisms for the treatment of tendinopathy have not been elucidated.

Impact of Heterosigma akashiwo on the environmental behavior of microplastics: Aggregation, sinking, and resuspension dynamics.

Aggregation processes of microalgae have significant effects on the vertical distribution of microplastics (MPs) in the marine environment. This study explored how the harmful microalga Heterosigma akashiwo affects the aggregation and sinking characteristics of four types of MPs: low and high-density polyethylene (PE) spheres, and small and large polypropylene (PP) fragments. The aggregation of MPs was primarily driven by extracellular polymeric substances (EPS) rather than direct attachment to the cells, contributing to their sinking.

A Comparative Study of Intense Pulsed Light with Two Different Filters in Meibomian Gland Dysfunction: A Prospective Randomized Study.

To compare the long-term efficacy and safety of intense pulsed light (IPL) treatments using a 590-nm and an acne filter. In this prospective, randomized, paired-eye trial study, 30 patients with moderate and severe meibomian gland dysfunction (MGD) were followed up for at least one month after their last treatment. Group A received IPL treatment with an acne filter, a type of notch filter that blocks wavelengths between 600 and 800 nm, allowing IPL to emit wavelengths between 400-600 nm and 800-1200 nm.

Qualitative Elicitation of Physical Activity Salient Beliefs Among Turkish Adolescent Girls.

Background: This study aims to investigate salient beliefs toward physical activity by gathering qualitative data through open-ended questions among high school-aged female adolescents in Turkey.

Methods: A sample of 259 Turkish high school students, aged between 14 and 17, were randomly selected to participate in this study. Open-ended questions address 3 main components of the Theory of Planned Behavior, attitudes, perceived control, and social norms.

Comparison of Short-Term Clinical Outcomes After Implantation of Two Monofocal, Aspheric Intraocular Lenses.

Objectives: This study compared the visual outcomes and optical quality of two monofocal, aspheric intraocular lenses (IOLs; CT LUCIA 621P, Carl Zeiss Meditec; Eyhance ICB00, Johnson & Johnson Vision) by evaluating visual acuity, contrast sensitivity, and higher-order aberrations 1 month post-cataract surgery.

Methods: In this retrospective, comparative study, 120 eyes (72 patients) that underwent cataract surgery with either CT LUCIA 621P (Lucia group) or Eyhance ICB00 (Eyhance group) implantation (60 eyes/group) were retrospectively investigated. Visual acuity at various distances and defocus curves were measured 1 month postoperatively.

Seasonal Water-Column Structure Drives the Trophic Niche of Fish Communities on a Temperate Continental Shelf.

In seasonally stratified marine environments, the dynamics of benthic-pelagic coupling plays a crucial role in shaping food web structures and fisheries production. We examined fish food web structures across three distinct shelf areas in the Southern Sea of Korea (SSK) during both stratified (summer) and mixed (spring) water conditions using stable isotopes of carbon (δC) and nitrogen (δN). In spring, fish communities exhibited a broader range of δC values compared with summer, indicating more diverse feeding strategies.

Effects of bladder neck sparing on continence outcomes of robotic-assisted radical prostatectomy: a systemic review and metaanalysis.

Restoration of postoperative urinary continence after robot-assisted radical prostatectomy (RARP) is affected by diverse factors. We compared the pad-free and positive margin rates of patients who underwent RARP with or without bladder neck sparing (BNS) for prostate cancer. During this systematic review and metaanalysis, we performed an electronic search of the Web of Science, Embase, Cochrane Central Register of Controlled Trials, and PubMed to find original articles comparing RARP with and without BNS for prostate cancer.

Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain.

Transplantation of induced pluripotent stem cell-derived neural cells represents a promising strategy for treating neurodegenerative diseases. However, reprogramming of somatic cells and their subsequent neural differentiation is complex and time-consuming, thereby impeding autologous applications. Recently, direct transcription factor-based conversion of blood cells into induced neural stem cells (iNSCs) has emerged as a potential alternative.

Initial experience of a novel ureteral silicon-covered metallic mesh stent in malignant ureteric obstruction: a single-center retrospective study.

Background: This study aimed to investigate initial experiences and outcomes of a retrograde inserted new silicone-covered metallic ureteric stent (Urexel™) for malignant ureteric obstruction.

Methods: We retrospectively reviewed the medical records for 12 consecutive patients who underwent Urexel™ stent placement for malignant ureteric obstruction from March 2020 to March 2021. The Urexel™ stent is a segmental metallic ureteric stent composed of a nitinol mesh covered with a silicone membrane.

Piezostrain-Driven Bidirectional Enhancement of Optical Synaptic Plasticity in Wafer-Scale Co-Phased Tin Selenide Layers.

Tin (Sn)-based two-dimensional (2D) materials exhibit intriguing mechanical and optoelectrical properties owing to their non-centrosymmetric crystallinity and tunable band structures. A judicious integration of these individually decoupled properties is projected to introduce unparalleled functionalities into them, which remain largely unexplored. Herein, we develop wafer-scale tin selenide (SnSe, 0 < < 1) 2D layers composed of thermodynamically stable coexisting phases of SnSe and SnSe with distinct functionalities and identify a strong interplay between their mechanical and optoelectrical characteristics.

Introducing Semiconducting-to-Metallic Transitions into Wafer-Scale 2D PdSe Layers by Low-Temperature Anion Exchange and Thickness Modulation.

Two-dimensional (2D) palladium diselenide (PdSe) layers are projected to exhibit a number of intriguing electrical properties such as semiconducting-to-metallic transitions. Precisely modulating their morphology and chemistry is essential for realizing such opportunities, which is particularly demanded on a large dimension under flexible processing conditions toward broadening their practical device applicability. Herein, we explore a wafer-scale growth of 2D PdSe layers and introduce semiconducting-to-metallic transitions into them at as low as 330 °C, a temperature compatible with a range of polymeric substrates as well as the back-end-of-line (BEOL) processes.

A Spectrophotometric Method to Determine Minimal Erythema Dose for Ultraviolet Radiation in Human Skin.

: Ultraviolet radiation (UVR) induces oxidative stress in the skin by generating reactive oxygen species (ROS), which can lead to inflammatory conditions including erythema (a sign of sunburn). This clinical study aims to develop an instrumental evaluation method to determine the minimal erythema dose (MED) for UVR. : Fourteen human subjects aged 27 to 57 years (48.

Epigenetic and Immune Profile Characteristics in Sinonasal Undifferentiated Carcinoma.

Introduction: Sinonasal undifferentiated carcinoma (SNUC) is a rare and highly aggressive malignancy originating in the nasal cavity and paranasal sinuses. Its pathogenesis and immune characteristics remain poorly understood.

Objectives: This study investigates the molecular aspects of SNUC, focusing on tumorigenesis and immunity.

Exploring the Strengths and Resilience of Siblings of People With Intellectual and Developmental Disabilities.

Background And Aims: Siblings play a crucial role in shaping and guiding the experiences of their brother or sister with a disability across the lifespan. However, little is known about the positive outcomes of their roles and experiences as siblings. Understanding the positive outcomes challenges stereotypes and the stigma associated with disabilities and allows for a more holistic view of sibling experiences.

Utility of transperineal template-guided mapping prostate biopsy in biopsy-naïve men with PI-RADS 1-2 on multiparametric magnetic resonance imaging.

Objective: To analyze the outcomes of transperineal template-guided mapping biopsy (TTMB) in biopsy-naïve men with multiparametric magnetic resonance imaging (mpMRI) results of Prostate Imaging-Reporting and Data System (PI-RADS) 1-2.

Patients And Methods: We retrospectively reviewed TTMB outcomes in biopsy naïve patients with PI-RADS 1-2 at a single center from August 2018 to May 2023. The patients' clinicopathologic data were reviewed, clinically significant prostate cancer (csPCa) detection rates were identified.

Nanomechanical thermometry for probing sub-nW thermal transport.

Accurate local temperature measurement at micro and nanoscales requires thermometry with high resolution because of ultra-low thermal transport. Among the various methods for measuring temperature, optical techniques have shown the most precise temperature detection, with resolutions reaching (~10 K). In this work, we present a nanomechanical device with nano-Kelvin resolution (~10 K) at room temperature and 1 atm.