Publications by authors named "Chung Hee Kim"
Article Synopsis
- This study examines the impact of bone marrow-derived mesenchymal stem cells (BM-MSCs) on mice with chronic colitis, revealing that BM-MSCs significantly reduce the severity of the disease and promote weight restoration.
- In the experiments, BM-MSCs were administered during the first cycle of colitis induced by dextran sulfate sodium (DSS), and the outcomes showed lasting benefits across multiple cycles of the treatment.
- The findings indicate BM-MSCs not only alleviate inflammation and tissue damage in the intestines but also enhance anti-inflammatory cytokine levels, suggesting their potential as a therapeutic option in chronic inflammatory conditions.
The effect of Lactobacillus plantarum genomic DNA on lipopolysaccharide (LPS)-induced mitogen-activated protein kinase (MAPK) activation, nuclear factor-kappa B activation, and the expressions of tumor necrosis factor-alpha, interleukin-1 receptor-associated kinase M, and the pattern recognition receptor were examined. Pretreatment of p-gDNA inhibited the phosphorylation of MAPKs and nuclear factor-kappa B, and also inhibited LPS-induced TNF-α production in response to subsequent LPS stimulation. L.
View Article and Find Full Text PDFAn EtOAc-soluble partition of the MeOH extract of a branch of Tetracera scandens (Dilleniaceae family) was subjected to a glucose-uptake assay, which led to the isolation and identification of five isoflavones of previously known structure namely, genistein (1), its derivatives 3',5'-diprenylgenistein (2), 6,8-diprenylgenistein (3), derrone (4) and alpinumisoflavone (5). Of these, compounds 2--5 exhibited significant glucose-uptake activity in basal and insulin-stimulated L6 myotubes. The findings from adenosine monophosphate-activated kinase (AMPK) activation and glucose transport protein4 (GLUT4) and GLUT1 over-expression revealed certain characteristics of compounds 2--5.
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