Hydrogen sulfide alleviates endothelial glycocalyx damage and promotes placental angiogenesis in rats exposed to cigarette smoke.

Our previous study has shown that hydrogen sulfide (HS) can attenuate cigarette smoke exposure (CSE)-induced placental injury in rats. This study investigated whether HS alleviates CSE-induced endothelial glycocalyx (eGC) impairment and promotes placental angiogenesis in rats. Twenty-four pregnant rats were randomly divided into four groups: control, NaHS (a donor of HS), CSE, and CSE + NaHS.