Statistical Analysis on Threshold of Haemoglobin A1C (HBA1c) for Diabetes Diagnosis and the Relationship Between HBA1c and Plasma Glucose Concentrations in Chinese Diabetic High-Risk Groups.

Background: The goal is to evaluate the threshold of hemoglobin A1C (HBA1c) for screening test among Chinese patients with diabetes and high-risk groups in the endocrinological department and identify the relationship between HbA1c and plasma glucose.

Methods: Experimental design: This study is based on the data selected from patients without clinical intervention enrolled in the Endocrinology Department and Admission Office in our hospital. It uses the four-point plasma glucose modeling and trapezoidal integration method to analyze the relationship between HbA1c and each plasma glucose threshold in an oral glucose tolerance test (OGTT).

Optimal cut-off points of fasting plasma glucose for two-step strategy in estimating prevalence and screening undiagnosed diabetes and pre-diabetes in Harbin, China.

To identify optimal cut-off points of fasting plasma glucose (FPG) for two-step strategy in screening abnormal glucose metabolism and estimating prevalence in general Chinese population. A population-based cross-sectional study was conducted on 7913 people aged 20 to 74 years in Harbin. Diabetes and pre-diabetes were determined by fasting and 2 hour post-load glucose from the oral glucose tolerance test in all participants.

Body mass index and susceptibility to knee osteoarthritis: a systematic review and meta-analysis.

Objective: Excess bodyweight, expressed as increased body mass index, is associated with osteoarthritis risk, especially in weight bearing joints. However, the strength of the association was inconsistent. The study was conducted to quantitatively assess the association between body mass index and the risk of knee osteoarthritis and investigate the difference of the strength stratified by sex, study type and osteoarthritis definition.

The relationship between body mass index and hip osteoarthritis: a systematic review and meta-analysis.

Objective: Body mass index, a measure of relative weight, is increasingly recognized as an important risk factor for osteoarthritis, especially in weight bearing joints. The objective was to assess the association between body mass index and hip osteoarthritis susceptibility and investigate the difference between sex, study type and osteoarthritis definition.

Methods: We did electronic searches of Medline, Embase and Cochrane library from the commencement to December 2009.