Preliminary risk assessment of in-vessel leakage accident in ITER.

The ITER project is one of the largest international cooperative scientific projects in the world, aiming to verify the feasibility of magnetic confinement controlled nuclear fusion technology and provide a technical basis for the subsequent construction of fusion energy power stations. The success or failure of ITER will greatly affect the commercialization process of fusion energy. The probabilistic safety assessment (PSA) was a powerful means to evaluate the risk and reliability of nuclear facility and achieved great success in safety assessment of fission power plants.

Comparative Experimental Study of Fracture Conductivity of Carbonate Rocks under Different Stimulation Types.

Carbonates have great potential for development, but the use of propped hydraulic fracturing or acid fracturing stimulation types alone has limited effectiveness. This study collected four sets of rock samples from three carbonate reservoirs: dolomite, limy dolomite, and limestone. The laboratory analysis focuses on propped hydraulic fracturing, acid fracturing, and acid fracturing plus proppants of these rock types.

Mutational landscape of thymic epithelial tumors in a Chinese population: insights into potential clinical implications.

Background: Thymic epithelial tumors (TETs) are a heterogeneous group of rare malignancies which may be devastating, difficult to treat, and for which treatment options are limited. Herein, we investigated the comprehensive genomic alterations of TETs in a Chinese population for providing clinical management, especially targeted therapy.

Methods: Comprehensive genomic profiling (CGP) was performed with DNA targeted sequencing of cancer-associated genes (CSYS) from a cohort of 40 Chinese TET patients.

miR-124 inhibits progression of hepatocarcinoma by targeting KLF4 and promises a novel diagnostic marker.

Hepatocarcinoma is one of the most lethal malignancy haunting the Chinese population, which is partially due to the difficulties in diagnosis at an early stage. The search for a biomarker that could signify the presence and progress of hepatocarcinoma is never ended. MicroRNAs are 22-nt RNAs that could bind to 3' UTR of target mRNAs, mediating degradation of mRNAs or inhibiting the translation.