Publications by authors named "ChunQing Gao"

Article Synopsis
  • Oncolytic vaccinia viruses (VV) are being explored as effective cancer treatment methods, with a focus on a modified strain called oncoVV-CLEC2A that incorporates a human gene.
  • This modified virus shows promise in inhibiting the growth of various human cancer cell lines, including those for colorectal and lung cancer, by enhancing its viral replication.
  • The study also reveals that oncoVV-CLEC2A stimulates the immune response by promoting cytokine production and activating natural killer cells, which could help develop new cancer therapies.
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We demonstrate the direct generation of single-frequency switchable orbital angular momentum (OAM) modes in a 1 µm wavelength range using a Nd:YVO microchip laser. The 808 nm laser diode pump beam is shaped into annular through an axicon associated with a lens. By adjusting the diameter and power of the annular pump beam, various OAM modes with different mode volumes can oscillate inside the Nd:YVO microchip.

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Analyzing the orbital angular momentum (OAM) distribution of a vortex beam is critical for OAM-based applications. Here, we propose a deep residual network (DRN) to model the relationship between characteristics of the multiplexed OAM beam and their complex spectrum. The favorable experimental results show that our proposal can obtain both the intensity and phase terms of multiplexed OAM beams, dubbed complex spectrum, with a wide range of OAM modes, varying in intensity, phase ratio, and mode intervals at high accuracy and real-time speed.

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1.6 µm high-order vortex modes carrying orbital angular momentums (OAMs) play significant roles in long-range Doppler lidars and other remote sensing. Amplification of 1.

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A 1645-nm single-frequency vortex beam with narrow linewidth from an Er:YAG nonplanar ring oscillator (NPRO) using an annular pump beam is demonstrated. The pump beam from a 1532-nm fiber laser is shaped to an annular beam by an axicon. The Er:YAG NPRO generates a 1.

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Optical vortex array has drawn widespread attention since the boom of special applications such as molecular selecting and optical communication. Here, we propose an integrated phase-only scheme to generate multiple multiplexed vortex beams simultaneously, constituting a multiplexed vortex state array, where the spatial position, as well as the corresponding orbital angular momentum (OAM) spectrum, can be manipulated flexibly as desired. Proof-of-concept experiments are carried out and show a few different multiplexed vortex state arrays that fit well with the simulation.

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Coherent Doppler wind lidar (CDWL) is used to measure wind velocity distribution by using laser pulses. However, the echo signal is easily affected by atmospheric turbulence, which could decrease the effective detection range of CDWL. In this paper, a variation modal decomposition based on honey badger algorithm (VMD-HBA) is proposed and demonstrated.

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We report a single-frequency Q-switched Er:YAG all-solid-state laser with a pulse repetition rate of up to 10 kHz. The single-frequency feature is ensured by injecting the seed laser into a Q-switched ring cavity, and the pulse repetition rate is increased by combing the Pound-Drever-Hall method and optical feedback. Peak power of 4.

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Beams carrying orbital angular momentum (OAM) already play significant roles in many domains. Here we propose a practical design of an OAM beam splitter based on a single phase-only multi-ring azimuthal-quadratic diffraction optical element that can sort different OAM components into various spatial positions, and OAM state probing is also achieved. The performance is demonstrated through proof-of-principle experiments and shows favorable results.

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Orbital angular momentum (OAM) is one of multiple dimensions of beams. A beam can carry multiple OAM components, and their intensity weights form the OAM spectrum. The OAM spectrum determines complex amplitude distributions of a beam and features unique characteristics.

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A denoising method based on singular value decomposition (SVD) and variational mode decomposition (VMD) is proposed for wind lidar. Utilizing the covariance matrix based lidar signal simulation model, the performance of VMD, SVD, and VMD-SVD is evaluated. The results show that the VMD-SVD method is of better performance, and the output signal-to-noise ratio (SNR) is about 12 dB at the input SNR of -9.

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Optical vortex arrays (OVAs) have successfully aroused substantial interest from researchers for their promising prospects ranging from classical to quantum physics. Previous reported OVAs still show a lack of controllable dimensions which may hamper their applications. Taking an isolated perfect optical vortex (POV) as an array element, whose diameter is independent of its topological charge (TC), this paper proposes combined phase-only holograms to produce sophisticated POV arrays.

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A wavelength tunable single-longitudinal-mode (SLM) Er:YAG ring laser around 1.6 µm is demonstrated. By using an acousto-optic modulator (AOM) to force unidirectional operation, up to 10.

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A laser beam lattice from tailoring spatial dimensions of lights is a kind of structured optical field, which already have found many applications in lots of domains. Here we propose a geometric phase element made from polymerized liquid crystals to transform Gaussian beams into a 64×64 beam lattice with high performance. Different from other geometric phase elements, the proposed element can introduce identical phase modulations for any polarizations, indicating that the beam lattice could be well generated with arbitrary incident homogeneous polarizations but not limited to specific circular polarizations.

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A resonantly pumped Er:YAG vector laser emitting at 1645 nm with selective polarization states is demonstrated. A compact five-mirror resonator incorporated a pair of quarter-wave plates (QWPs), and a pair of q-plates (QPs) is employed. Cylindrical vector beams of all states on a single high-order Poincaré sphere could be obtained by rotating the QWPs and QPs relatively.

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We present an injection-seeding -switched 1645 nm Er:YAG ceramic laser with high frequency stability and energy stability by combining the injection-seeding technique and Pound-Drever-Hall technique. 10.31 mJ single-frequency pulses with optimal frequency stability (525 kHz) and relative energy stability (0.

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A 4-pass structure Er:YAG MOPA system at 1645 nm is theoretically and experimentally investigated. In accordance with the theoretical analysis, the 4-pass structure significantly improved the amplification performance. The highest gain is about 4 with 1 mJ incident seed energy.

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Solid-state single-frequency lasers around 1.6 µm are ideal sources for coherent Doppler wind lidars (CDWLs). A CDWL system with 1645 nm sing-frequency, injection-seeded Er:YAG ceramic laser is demonstrated.

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The vector vortex beams (VVB) possessing non-separable states of light, in which polarization and orbital angular momentum (OAM) are coupled, have attracted more and more attentions in science and technology, due to the unique nature of the light field. However, atmospheric transmission distortion is a recurring challenge hampering the practical application, such as communication and imaging. In this work, we built a deep learning based adaptive optics system to compensate the turbulence aberrations of the vector vortex mode in terms of phase distribution and mode purity.

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Orbital angular momentum (OAM), a new dimension of photons, has potentials in lots of domains as high-dimensional data coding/decoding. Here we experimentally demonstrate a free-space data transmission system based on 8 bits multi-state OAM shift keying, where multiplexed optical vortices containing 8 various OAM states are employed to constitute 8 bits binary symbols. In the transmitter, the data coding of OAM shift keying is realized by switching a series of special-designed holograms.

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Multicasting is necessary when distributing signals between multiple users. In this Letter, we demonstrate an orbital angular momentum (OAM) encoding-based free-space one-to-many multicasting link, where digital signals are encoded into a series of time-varying OAM states and transmitted from one transmitter to multiple receivers with various locations. Moreover, encoding N various signals simultaneously in one transmitter and sending them at the same time to N various receivers separately, is also demonstrated.

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A high pulse repetition frequency (PRF) single-frequency Er:YAG ceramic ring laser is demonstrated. A double-ceramics ring cavity both end-pumped by a 1532-nm fiber laser is also used to increase the pulse energy. The maximum single-frequency output energies are 21.

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The angular acceleration of a spinning object can be estimated by probing the object with Laguerre-Gauss (LG) beams and analyzing the rotational Doppler frequency shift of returned signals. The frequency shift is time dependent because of the change of the rotational angular velocity over time. The detection system is built to collect the beating signals of LG beams back-scattered from a non-uniform spinning body.

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A high-energy, single-frequency, injection-seeded, Q-switched Er:YAG laser oscillating at 1645 nm is demonstrated. For obtaining high output energy, a double-crystals-end-pumping architecture is utilized. The maximum output energies of single-frequency pulses are 12.

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