Publications by authors named "ChunChau Sze"
Article Synopsis
- A novel microfluidic chip was developed for isolating DNA or RNA from as few as one bacterial cell in very small sample volumes (1 μl to 125 nl), making it useful for clinical and biological applications.
- The process uses phase partitioning with an organic layer to significantly enhance nucleic acid recovery yields, achieving up to 10 times more RNA or DNA compared to conventional methods.
- The chip allows for on-chip quantitative PCR analysis directly in the microwells, facilitating high-throughput extraction and analysis of nucleic acids from single bacterial cells, ideal for automated pathogen detection and gene expression studies.
