Recombinant human epidermal growth factor combined with vacuum sealing drainage for wound healing in Bama pigs.

Background: Vacuum sealing drainage (VSD) and epidermal growth factor (EGF) both play an important role in the treatment of wounds. This study aims to explore the effects of the combination of VSD and EGF on wound healing and the optimal concentration and time of EGF.

Methods: We tested the proliferation and migration capacity of HaCaT and L929 cells at different EGF concentrations (0, 1, 5, 10, and 100 ng/ml) and different EGF action times (2, 10, and 30 min).

Brain activation patterns during unilateral premolar occlusion.

Objective: To observe the characteristics of brain activation during unilateral premolar occlusion.

Methods: Functional magnetic resonance imaging was collected from 10 healthy volunteers during occlusion of the left first premolar (L1), left second premolar (L2), and right first premolar (R1). The brain activation patterns were analyzed, and the primary sensorimotor cortex, supplementary motor area, insula, thalamus, and prefrontal cortex were chosen as regions of interest.

[Three-dimensional finite element analysis of effect of root canal taper and post on tooth stress distribution].

Objective: To evaluate the effect of root canal taper and post on tooth stress distribution.

Methods: Three-dimensional finite element models of human mandibular first molar with root canals prepared with 35# K file, ProTaper and Profile were established. The tooth were restored with fiber-resin, stainless steel and silver amalgam posts respectively.

[Correlation of ornidazole concentration in saliva and serum of healthy volunteers].

Objective: To investigate the distribution of ornidazole in the salivary and serum of healthy adults and explore the feasibility of monitoring serum drug concentration with salivary.

Methods: Six volunteers received a single dose of 0.6 g ornidazole via intravenous infusion.

[Influence of soft-start irradiation on polymerization shrinkage stress of universal hybrid composite resins].

Objective: To compare the difference between soft-start curing mode and standard curing mode in polymerization shrinkage stress of universal hybrid composite resins and to study effect of the soft-start curing mode on the decrease of shrinkage stress.

Methods: Three universal hybrid resins (A: Charisma, B: TPH Spectrum, and C: Esthet-X) were respectively filled in cavities (4 mm in diameter) of epoxide resin disks, 16 specimens of each. Off them, eight of the specimens for each composite resin were exposed using soft-start mode and the other eight using standard mode.