Publications by authors named "Chun-yin Yu"
Article Synopsis
- Prolonged mitotic arrest can trigger mitotic catastrophe, which is a promising strategy for cancer treatment, highlighting the role of antiapoptotic proteins like BCL-XL in managing cell survival during this phase.
- Compensatory changes in the expression of related proteins BCL2 and MCL1 complicate research, prompting the use of a specialized system to silence BCL-XL just before mitosis.
- The study concludes that BCL-XL is crucial in preventing apoptosis during mitotic arrest, even more so than BCL2, and that its loss leads to cell death primarily through a BAX-dependent mechanism, while MCL1 can help buffer this effect.
[Polymorphism of DXYS267 locus and application of its Y-specific single nucleotide substitutions].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
October 2005
Objective: To investigate the polymorphism of DXYS267 locus in China Han population and find the application and characters of its Y-specific single nucleotide substitutions.
Methods: The locus was analyzed by PCR and PAGE in silver-staining. The Y-specific STR was amplified with newly designed primers according to the Y-specific single nucleotide substitutions.