Publications by authors named "Chun-ren Wang"

Article Synopsis
  • The study focuses on the mitochondrial genome of a trematode parasite from wood frogs, marking the first complete sequencing for the family Pleurogenidae, which is significant due to high infection rates in these frogs and their ecological importance.* -
  • The mitochondrial genome is circular and comprises 15,043 base pairs with 36 genes, including 12 protein-coding genes, and shows a strong bias towards adenine and thymine (63.75% A+T content).* -
  • Phylogenetic analysis indicates that this trematode is more closely related to Prosthogonimidae than to Eucotylidae, providing valuable genetic data for future research on Xiphidiata trematodes.*
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Tabanids, commonly known as horseflies and belonging to the family Tabanidae, are blood-feeding arthropods (BFA) found worldwide. They are known for their ability to mechanically and biologically transmit various animal pathogens. Tabanids are potential vectors for diseases such as spp.

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  • - The study investigates the global prevalence and risk factors of fascioliasis (liver disease caused by the Fasciola parasite) in humans and domestic ruminants, finding that 17% of cattle, 13% of sheep, and 5% of humans are affected.
  • - Researchers analyzed 4422 articles, narrowing it down to 371 relevant studies, and employed various statistical methods to assess prevalence and identify risk factors, particularly focusing on altitude and age.
  • - The findings highlight the widespread nature of fascioliasis and emphasize the urgent need for targeted prevention strategies based on identified risk factors.
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  • - The study examines how the parasite Toxoplasma gondii alters host RNA modification profiles to promote its own replication during infection.
  • - Researchers used advanced techniques to analyze RNA modifications in mouse liver, spleen, and serum, finding significant changes, especially in the liver, during acute infection.
  • - The results suggest that these RNA modifications can affect the stability of tRNA and protein translation, enhancing our understanding of host response mechanisms to parasitic infections.
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  • The study investigates the prevalence of important diarrheal protozoan pathogens in cattle fecal samples collected from Heilongjiang Province, highlighting their global health risks to humans and animals.
  • The research sampled 1,155 cattle, revealing infection rates of 5.5% for one protozoan species, 3.8% for another, and 6.5% for a third, with several genetic variants identified among them.
  • Findings indicate that some protozoan species are zoonotic, meaning they can be transmitted from animals to humans, which raises public health concerns in the affected areas.
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Prosthogonimiasis poses a threat to the reproductive system of poultry and wild birds, which are the definitive hosts of the parasite causing this disease. However, the parasite infection of the second intermediate host (dragonfly), the primary vector of this pathogen, is rarely reported. In this study, the prevalence of Prosthogonimus infection in dragonflies was investigated from June 2019 to October 2022 in Heilongjiang Province, northeast China.

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  • Trematodes are intestinal flukes that can infect various hosts and cause economic losses globally, but there's limited molecular research on them.
  • This study focused on the mitochondrial genome of a specific trematode from red pandas, revealing it has 14,642 base pairs and contains 12 protein-coding genes among other genetic components.
  • The findings enhance existing mitochondrial genome data and could support future studies on the taxonomy and genetics of related trematodes.
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Article Synopsis
  • - The study focuses on the sequencing of mitochondrial genomes of two important trematode parasites affecting wood frogs, revealing complete genome lengths of 14,210 bp and 14,179 bp, consisting of 36 functional genetic subunits.
  • - Both parasites exhibit identical gene arrangements and similar characteristics to other related trematodes, with specific initiation and termination codons observed in the protein-coding genes.
  • - Phylogenetic analysis indicates that these parasites are closely related, with distinctions made between amphibian and ruminant flukes, suggesting the significance of this research for future taxonomy and genetics studies in trematodes.
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  • * This study sequenced the complete mitochondrial genomes of Aedes vexans and Ochlerotatus caspius, finding that their genomes are circular and contain essential genes and structures, contributing to our understanding of their biology.
  • * Phylogenetic analysis showed that A. vexans is closely related to other Aedes species, and O. caspius aligns with Ochlerotatus species, confirming their classification and providing resources for future research on this diverse tribe.
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  • - Clonorchiasis, caused by the liver fluke Clonorchis sinensis, poses risks for serious liver diseases, including cholangiocarcinoma, but its exact mechanisms and diagnostic markers are still not well understood.
  • - A study involving 18 rabbits assessed the impact of C. sinensis infection on liver function and identified various biochemical changes and metabolites at multiple time points post-infection using advanced testing methods.
  • - The findings revealed significant changes in liver function markers and identified several potential noninvasive biomarkers, like AST and GGT, useful for diagnosing C. sinensis infection effectively.
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Prosthogonimus cuneatus and Prosthogonimus pellucidus (Trematoda: Prosthogonimidae) are common flukes of poultry and other birds which can cause severe impacts on animal health and losses to the poultry industry. However, there are limited studies on the molecular epidemiology, population genetics, and systematics of Prosthogonimus species. In the present study, the complete mitochondrial (mt) genomes of P.

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  • A significant parasitic nematode of cranes, classified as part of the Spirurina suborder, has a controversial classification that has persisted for over a century.
  • The complete mitochondrial genome of this nematode was sequenced, revealing a circular structure with 13,709 bp, containing 12 protein-coding genes and high AT content similar to other Spirurina species.
  • Phylogenetic analyses showed that this nematode is more closely related to Spiruroidea than to Thelazioidea, providing valuable genetic markers for future research on Spirurina nematodes.
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  • * The data indicated that free-range cattle showed a higher prevalence (34.4%) compared to those in intensive farming (22.3%), and infection rates were higher prior to 2013 (36.1%) than afterward (33.6%).
  • * Among different Theileria species, T. annulata and T. sergenti had the highest prevalence, and various geographic factors—like climate—were linked to infection rates, suggesting the need
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is a neglected zoonotic parasite of the gallbladder and bile duct of poultry, mammals, and humans. It has been widely reported in Asian, including China, Japanese, and Korea, where it is a potential threat to public health. Despite its significance as an animal and human pathogen, there are few published transcriptomic and proteomics data available.

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Clonorchiasis, which is caused by , is an important foodborne disease worldwide. The excretory-secretory products (ESPs) of play important roles in host-parasite interactions by acting as causative agents. In the present study, the ESPs and sera positive for were collected to identify proteins specific to the sera of (i.

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is a widespread pathogen that is known for its harmful effects on the health and productivity of ruminant animals. To identify the proteins present in all periods of infection with but not in those with by shotgun liquid chromatography-tandem mass spectrometry (LC-MS/MS), we collected the ESPs and sera of and . In this study, the sheep were artificially infected with and the sera were collected at five different periods: 3 days post-infection (dpi), 7 dpi, 21 dpi, 63 dpi, and 112 dpi.

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Toxoplasmosis is a zoonotic disease caused by Toxoplasma gondii, which is widespread in warm-blooded animals and humans. Currently, many studies regarding T. gondii infection in sheep have been published worldwide.

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Coronocyclus labiatus and Cylicodontophorus bicoronatus are two significant horse parasitic nematodes which are classified into subfamily Cyathostominae, family Strongylidae, however, the classification of these nematodes has been controversial for more than a century. Mitochondrial (mt) genomes are considered valuable sources for parasite taxonomy, population genetics, and systematics studies. In the present study, the mt genomes of Co.

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, an intracellular zoonotic parasite, can infect humans and various animals worldwide. Wild rodents plan an important role as intermediate hosts of . Some studies on from wild rodents have been published, but the investigation data of in wild rodents in China are limited.

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Cryptosporidium spp. and Enterocytozoon bieneusi are two important zoonotic pathogens that can cause diarrhea and other gastrointestinal illnesses in humans and animals. However, the prevalence and genotype of the parasites in Longjiang Wagyu cattle in Heilongjiang Province, Northeast China have not been reported.

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  • * A systematic review and meta-analysis of studies published between 1976 and 2020 revealed an overall prevalence of 30.5% for C. sinensis metacercariae in fish, with the highest rates observed in China (35.1%) and the lowest in Vietnam (8.4%).
  • * Factors such as climate, water source, and publication date were significant in influencing prevalence rates, indicating a pressing public health issue related to this parasite in the region.
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Cyathostomins are one kind of the most important parasites in equids. Cylicostephanus minutus is a member of the subfamily Cyathostominae. In the present study, we determined the complete mitochondrial (mt) genomes from four Cs.

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Toxoplasma gondii infecting virtually all warm-blooded animals, including humans, is an intracellular protozoan parasite. The immunocompromised patients or pregnant women infected by Toxoplasma usually can cause encephalitis or abortion. Deer are also the important intermediate host of the parasite and people can be infected by ingesting the undercooked venison.

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is an important protozoan parasite that can infect a range of animals. Cats are the most important definitive hosts for . Therefore, an assessment of the level of infection in cats is of public health importance.

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Both Clonorchis sinensis and Metorchis orientalis are the fish-borne zoonotic trematodes, and have a wide distribution of southeastern Asia, especially in China. Due to the similar morphology, life cycle, and parasitic positions are difficult to differentiate between both metacercariae. In the present study, the complete rDNA sequences of five C.

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