Publications by authors named "Chun-ming Dong"

Article Synopsis
  • - Allergic diseases, particularly shrimp allergy, are significant health concerns today, with a focus on key allergens like tropomyosin and arginine kinase, and their roles in different immune response reactions, including IgE-mediated hypersensitivity and non-IgE-mediated reactions.
  • - Research into cross-reactivity highlights connections between shrimp allergies and other animal allergies, leveraging bioinformatics tools to better understand allergen molecular features through methods such as homology analysis and epitope prediction.
  • - Advancements in treatment and diagnosis, including immunotherapy, gene editing, and innovative detection technologies, aim to reduce allergic sensitivity and improve allergy management, offering new strategies for effective prevention and control of food allergies.
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Article Synopsis
  • * By utilizing metaproteomic and 16 rRNA amplicon sequencing methods, researchers found that microbial communities showed clear vertical connectivity in composition and function from the surface to depths of 3000 meters.
  • * Key microbial groups like Oceanospirillales, Alteromonadales, and Rhodobacterales were identified, with findings indicating that surface microbes influence deep-sea biochemistry by enhancing protein expression related to metabolism and environmental stress.
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Cancer is an important chronic non-communicable disease that endangers human health and has become the main cause of death of residents around the world in the 21st century. At present, most of the mature treatment methods stay at the level of cell and tissue, which is difficult to fundamentally solve the problem of cancer. Therefore, explaining the pathogenesis of cancer at the molecular level becomes the answer to the key problem of cancer regulation.

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Phenol and phenolic compounds are main pollutants in wastewater of coking factories. To identify the bacteria responsible for phenol removal in the activated sludge of a coking factory, we isolated bacteria from the sludge directly or after enrichment. From two samples from the aerobic and anaerobic pools, 28 strains belonging to 28 species of 20 genera were obtained after identification with BOX-PCR and further 16S rDNA sequence analyses.

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Objective: To assess the feasibility of the 10 microg recombination yeast hepatitis B vaccine in the expanded applicable population group aged 5 - 18.

Methods: People with both HBsAg and anti-HBs negative were selected to take two-stage clinical experiment and the safety and immunogenicity were observed. Safety observation was conducted in 925 subjects, while 568 for immunogenicity.

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Objective: To introduce exponent curve model methods in the study of the hepatitis B vaccine antibody level.

Methods: After the China made vaccine of hepatitis B DNA recombinant yeast derived vaccine (YDV) had been carried out for 5 years, data on the anti-HBsAg's titer were used to construct an exponent curve model. When the vaccination program had been carried out for 8 years, the predicating results of the model were further tested by observed number.

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