Publications by authors named "Chun-Ying Wong"
Capillary leak syndrome (CLS) is a severe complication of allogeneic hematopoietic stem cell transplantation (HSCT) characterized by weight gain, generalized edema, hypotension, and hypoalbuminemia. The primary pathogenesis is injury of the capillary endothelium resulting in a loss of intravascular fluid into the interstitial space. Treatment is limited to vascular endothelial growth factor withdrawal and systemic corticosteroids.
View Article and Find Full Text PDFThere are few studies addressing the longitudinal analysis of serum IgE levels and its impact to the development of atopic diseases in early childhood. We investigated 170 children who regularly followed up at our clinic for 4 years in a birth cohort study with at least 3 time-points of serum samples. The pattern of total serum IgE levels from 6 months to 4 years of age was clustered using K-means method in R software.
View Article and Find Full Text PDFArticle Synopsis
- - Nasopharyngeal carcinoma (NPC) is a cancer that starts in the nasopharynx and is linked to the Epstein-Barr virus (EBV), with high rates of incidence and death in Southeast Asia; early detection is crucial for better outcomes.
- - The study evaluated various existing and new biomarkers for NPC; it found that the BamHI-W 76 bp biomarker showed high sensitivity (96.7% for Stage I NPC) and good specificity, making it an effective option for early detection.
- - The research suggests that combining certain biomarkers could enhance detection accuracy and that specific biomarkers can also indicate patient prognosis, ultimately aiming to improve NPC screening and reduce the burden of late diagnoses.