Publications by authors named "Chun-Yan Tian"

Objective: TPMS porous structures have adjustable stiffness, a smooth surface, and highly connected pores, which help avoid stress concentration within the dot-matrix structure and promote cell adhesion and proliferation. A cervical interbody cage based on this type of porous structure was designed and fabricated, and its mechanical properties and biocompatibility were evaluated.

Methods: TPMS porous structures have adjustable stiffness, a smooth surface, and highly connected pores, which help avoid stress concentration within the dot-matrix structure and promote cell adhesion and proliferation.

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Article Synopsis
  • * Genetic engineering, particularly methods like CRISPR, is being used to improve sugarcane's resilience and productivity under challenging conditions.
  • * The review discusses how innovative genetic techniques can create sugarcane varieties that are better equipped to handle stress and ultimately enhance sugarcane farming.
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This study assessed the effectiveness and safety of Chinese herbal medicine Ping Chuan Ke Li (PCKL) for the treatment of patients with mild/ moderate persistent asthma.A total of 108 eligible patients with persistent asthma were included and were divided into a treatment group and a control group in this retrospective study. All 108 patients underwent oral montelukast.

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The C2H2 zinc finger protein family, one of the largest families of transcription factor/transcriptional regulator in mammal, arose from a small ancestral group of eukaryotic zinc finger transcription factors through many repeated gene duplications accompanied by functional divergence. As the biggest subfamily of C2H2 zinc finger protein family, Kruppel-associated box-containing zinc finger proteins (KRAB-ZFPs) appeared at the period oftetrapod, expand rapidly along with species evolution, and take about 60% of the total C2H2 zinc finger proteins in human. During species evolution, the DNA binding ability of KRAB-ZFPs is changed while the KRAB-ZFPs-mediate transcriptional repression ability maintains stable under the evolution pressure.

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Chronic obstructive pulmonary disease (COPD) is a common respiratory disease, but seriously threatens to patients' body and mind. Constitutions of Chinese medicine (CM) are closely relat- ed to diseases. Individuals with different constitutions of CM have different responses to the same envi- ronment and the same pathogenic factor.

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Objective: To evaluate the value of hip MR for diagnosing acetabular labrum tears, and to further compare the diagnostic performances of conventional MR with MR arthrography in acetabular labrum tears.

Methods: 90 patients undergoing both hip MR examination and subsequent hip arthroscopy were retrospectively evaluated. Of these patients, 34 accepted both conventional MR and MR arthrography; while the other 56 only underwent conventional MR examination.

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Purpose: The purpose of this study is to compare MR arthrography in abduction and external rotation (ABER) position with conventional MR arthrography in neutral position for the detection and further classification of anteroinferior labroligamentous lesions.

Materials And Methods: Two hundred and twenty-nine cases of shoulder MR arthrography with subsequent arthroscopy were retrospectively evaluated. All MR arthrograms in ABER position and neutral position were independently assessed by two radiologists who were blinded to the arthroscopic findings.

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Objectives: To clarify the morphological features of normal meniscal roots on magnetic resonance (MR) imaging with an isotropic 3D proton density-weighted (PDW) sequence.

Materials: 3D PDW MR was performed in sixty-two patients at 3T before knee arthroscopy. MR images of 34 normal medial menisci and 33 intact lateral menisci confirmed by arthroscopy were retrospectively evaluated.

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Purpose: To evaluate the feasibility of using a fat-suppressed 3D volumetric interpolated breath-hold examination (VIBE) sequence in magnetic resonance (MR) arthrography as a substitute for nonarthrographic multislice computed tomography (MSCT) in detecting glenoid bone lesions.

Materials And Methods: Fat-suppressed 3D VIBE MR arthrography and MSCT were performed in 56 patients (46 male, 10 female; age range, 14-51 years; mean age, 26 years). Based on the results of MSCT, the sensitivity and specificity of fat-suppressed 3D VIBE images for detection of bony Bankart lesion and glenoid bone loss were determined.

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By using a neutral inner-salt-type dicarboxylate as coligand, a novel two-dimensional (2D) manganese(II) coordination polymer, [Mn(L)(N(3))]ClO(4) x 1/2 H(2)O (L = 1,3-bis(3-carboxylatopyridinium)propane), was synthesized, and characterized by X-ray crystallography and magnetic measurements. The compound contains uniform Mn(II) chains with simultaneous azide and carboxylate bridges between adjacent Mn(II) ions. The formally negative chains are interlinked by the positively-charged 1,3-bis(pyridinium)propane spacer, and the spiral conformation of the spacer imports intriguing helical features to the resulting 2D network, in which [MnL] helices are connected by sharing metal centers with alternating centro- and C(2)-symmetry.

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The asymmetric unit of the title compound, [Co(N(3))(2)(H(2)O)(4)]·C(14)H(12)N(2)O(4), comprises half of the cobalt(II) complex mol-ecule and a half of the 3,3'-dicarboxyl-ato-1,1'-ethyl-enedipyridinium mol-ecule. The Co(II) atom is located on an inversion centre and hence the complex mol-ecule adopts a centrosymmetric trans-octa-hedral geometry. The zwitterionic organic mol-ecule is also centrosymmetric with the centre of the C-C bond of the ethyl-ene moiety coinciding with an inversion centre.

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The ubiquitin protein ligase (E3) MDM2 (Murine double minute 2) possesses oncogenic activities. Overexpression of this protein enhances degradation and inactivation of the tumor suppressor p53. At least 7% of all human tumors exhibit inappropriate amplification of mdm2, whereas p53 gene remains in its wild-type configuration.

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A novel 2D coordination polymer consisting of ferromagnetic Ni(ii) chains with alternating double EO-azide bridges and (EO-azide)bis(carboxylate) triple bridges exhibits solvent-modulated metamagnetism, and the reversible dehydration/hydration processes are accompanied by significant changes in critical temperature, critical field and hysteresis.

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Leaves, the collective organ produced by the shoot apical meristem (SAM), are polarized along their adaxial-abaxial axis. In this study, we characterized two rice (Oryza sativa) allelic rolled-leaf mutants, rolled leaf 9-1 (rl9-1) and rl9-2, which display very similar phenotypes with completely adaxialized leaves and malformed spikelets. We cloned the RL9 gene by way of a map-based cloning strategy.

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Site- and state-specific lysine methylation of histones is catalyzed by a family of proteins including those contain the evolutionarily conserved SET domain. Research on histone methyltransferases is a part of epigenetics, which plays a fundamental role in heterochromatin formation, X-chromosome inactivation and transcription regulation. Aberrant histone methylation was linked to a number of developmental disorders and human disease including several carcinomas.

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The zinc finger proteins containing the Kruppel-associated box domain (KRAB) constitute the largest single family of transcriptional regulators in mammals. Many genes encoding members of this family are arranged in clusters. KRAB-containing proteins are characterized by the presence of 4 and over 30 C2H2 zinc-finger motifs and a KRAB domain near the amino terminus of the protein.

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To examine the binding sites of miyabenol C (Miy C) and kobophenol A ( Kob A) with estrogen receptor (ER), computer modeling was applied to determine 3D structure of Miy C and Kob A. Molecular docking of the components to ER was carried out to find the binding sites between them. PCR mutagenesis was used to change the structure of ER cDNA.

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Aim: To improve E-screen assay and make it more accurate to screen estrogenic compounds.

Methods: Estrogen receptor antisense RNA expression plasmid (pCASER) was constructed and introduced into MCF-7 with lipofectAMINE(TM), and positive clones were screened out with G418. PCR amplification was employed to identify whether estrogen receptor (ER) cDNA fragment had been inserted into MCF-7 cell genomes.

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