Publications by authors named "Chun-Wen Jia"
Background: The role of soluble interleukin-1 receptor type 2 (sIL-1R2) in acute myocardial infarction (AMI) remains undocumented. In the present study, we aimed to evaluate the possible associations of sIL-1R2 with left ventricular (LV) function, remodeling and future clinical events in the setting of AMI.
Methods: Circulating sIL-1R2 levels were quantified after percutaneous coronary intervention (PCI) on day 1 of hospital admission for 204 AMI patients, and upon enrollment of 204 healthy controls.
Article Synopsis
- A 16-year-old girl experienced syncope during a race, with significantly elevated troponin levels indicating potential heart issues, leading to a diagnosis of spontaneous coronary artery dissection (SCAD).
- Despite presenting with unusual symptoms for SCAD, the girl's condition worsened to cardiogenic shock, requiring urgent medical intervention including stenting of the left main coronary artery after confirming the diagnosis with imaging.
- The case emphasizes that SCAD should be considered in young, low-risk patients presenting with acute coronary syndrome symptoms, as timely diagnosis and treatment can lead to positive outcomes.
[Effect of atorvastatin on ACE2 expression in pressure overload induced cardiac hypertrophy in rats].
Zhong Nan Da Xue Xue Bao Yi Xue Ban
May 2008
Objective: To investigate the effect of atorvastatin on the expression of angiotensin converting enzyme 2 (ACE2) mRNA and its protein in hypertrophic myocardium in rats.
Methods: Suprarenal abdominal aortic coarctation was performed to create the pressure overload induced left ventricular hypertrophy model in rats.
Results: Rats were randomly divided into 5 groups: (1) normal control group (Group A); (2) normal control group treated with atorvastatin [(5 mg/(kg.