Publications by authors named "Chun-Rong Zhao"
Morphological Identification of TRPC7 in Cardiomyocytes From Normal and Renovascular Hypertensive Rats.
J Cardiovasc Pharmacol
February 2016
Article Synopsis
- The study investigated how TRPC7, a type of ion channel, is expressed in normal vs. hypertrophic heart cells.
- Using a model of renovascular hypertension in rats, researchers found that TRPC7 expression decreased significantly in hypertrophied cardiac tissue while another protein, PKC, increased.
- Treatment with losartan, an Ang II receptor blocker, not only reduced hypertension and heart enlargement but also helped restore TRPC7 levels, suggesting TRPC7's important role in heart function.
Abnormal expression of PER1 circadian-clock gene in oral squamous cell carcinoma.
Onco Targets Ther
December 2012
Background: The PER1 circadian-clock gene plays an important role in the regulation of many normal physiological rhythms in vivo. It has been revealed recently that abnormal expression of PER1 correlates closely with the occurrence and development of many cancers. However, the expression and significance of PER1 in oral squamous cell carcinoma (OSCC) remains unknown.
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