Discovery of -aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents and activating the Hippo signalling pathway.

Hippo signalling pathway plays a crucial role in tumorigenesis and cancer progression. In this work, we identified an , compound as an anti-gastric cancer agent, which exhibited potent antiproliferative ability with IC values of 0.36 μM (MGC-803 cells), 0.