Prediction of human triglyceride concentration based on quantum genetic-partial least squares algorithm and fluorescence spectroscopy.

It is an important subject with practical significance in modern medical testing about how to obtain various indicators in blood effectively and conveniently. In this essay, the prediction model of triglyceride (TG) concentration was studied based on the fluorescence spectrum of human serum. Firstly, the concept of effective signal intensity was proposed based on the results of wavelet decomposition that the noise signals of spectrum was mainly distributed in the first and second detailed components, and 280 nm was selected as the optimal excitation wavelength for modeling.

Doping dependence of the phase diagram in one-dimensional extended Hubbard model: a functional renormalization group study.

Using functional renormalization group method, we studied the phase diagram of the one-dimensional extended Hubbard model at different dopings. At half filling, variety of states strongly compete with each other. These states include spin-density wave, charge-density wave, s-wave and p -wave superconductivity, phase separation, and an exotic bond-order wave.

Activation of miR-34a-5p/Sirt1/p66shc pathway contributes to doxorubicin-induced cardiotoxicity.

The molecular mechanisms underlying anthracyclines-induced cardiotoxicity have not been well elucidated. MiRNAs were revealed dysregulated in the myocardium and plasma of rats received Dox treatment. MicroRNA-34a-5p (miR-34a-5p) was verified increased in the myocardium and plasma of Dox-treated rats, but was reversed in rats received Dox plus DEX treatments.

CircRNA_000203 enhances the expression of fibrosis-associated genes by derepressing targets of miR-26b-5p, Col1a2 and CTGF, in cardiac fibroblasts.

Circular RNAs (circRNAs) participate in regulating gene expression in diverse biological and pathological processes. The present study aimed to investigate the mechanism underlying the modulation of circRNA_000203 on expressions of fibrosis-associated genes in cardiac fibroblasts. CircRNA_000203 was shown upregulated in the diabetic mouse myocardium and in Ang-II-induced mouse cardiac fibroblasts.

Hsp90aa1: a novel target gene of miR-1 in cardiac ischemia/reperfusion injury.

The role of microRNA-1 (miR-1) in ischemia/reperfusion (I/R)-induced injury is not well illustrated. The present study aimed to investigate the expression and potential target of miR-1 in the myocardium of a rat model of I/R. The apoptosis of cardiomyocytes in the ischemic rat myocardium increased on day 1, then attenuated on day 3 and day 7 post-I/R.

[The long-term effect and associated factors of double embolization of bronchial artery in patients with lung tuberculosis and hemoptysis].

Objective: To investigate the long-term effect and the key factors associated with relapse of double embolization of bronchial artery in patients with lung tuberculosis and hemoptysis.

Methods: Fifty patients with lung tuberculosis and hemoptysis receiving the radiography and double embolization of bronchial artery (BAG + BAE) had been followed up for two years. The causes for hemoptysis relapse was determined, followed by specific treatment, and the effect was evaluated.