Publications by authors named "Chun-Ling Hu"
Article Synopsis
- Blood-brain barrier (BBB) disruption is a key factor in the development of ischemic stroke (IS), and the effects of neferine (Nef) on this disruption are not well understood.
- In studies using mice and brain cell models, Nef was shown to improve neurobehavioral functions, protect brain endothelial cells, and maintain BBB integrity by upregulating a protein called PGC-1α.
- Nef reduces oxidative stress and inflammation in brain cells, promoting the repair of the BBB during IS through a specific signaling pathway involving PGC-1α.
Background: Patients with chronic hepatitis B virus (HBV) infection are at high risk for progressing to decompensated cirrhosis and hepatocellular carcinoma (HCC). Although long-term treatment with nucleos(t)ide analogues (NAs) benefits patients with chronic hepatitis B (CHB), many develop HCC. Therefore, the clinical outcomes of patients CHB who undergo long-term treatment with NAs remain to be identified.
View Article and Find Full Text PDFObjective: To identify the active material of anti-hepatic fibrosis from Amydae Carapax.
Methods: Membrane separation technology was adopted to screen active fraction in Amydae Carapax, and the active components were isolated from the active fraction using gel chromatography and high performance liquid chromatography. The purified active components in Amydae Carapax were further analyzed using 4700 series time-of-flight mass spectrometer.
In this study, Lactobacillus paracasei subsp. paracasei NTU101 and Lactobacillus plantarum NTU 102 were used as starter to ferment soy-skim milk, and the optimal mixing ratio was evaluated. The influence of lactic acid bacteria (LAB)-fermented soy-skim milk on mucosal integrity in a gastric mucosal lesion rat model was also investigated.
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