Non-animal assessment of skin sensitization is a global trend. Recently, scientific efforts have been focused on the integration of multiple evidence for decision making with the publication of OECD Guideline No. 497 for defined approaches to skin sensitization.
View Article and Find Full Text PDFThis study elucidates the taxonomic position of in considering whether it belongs to or . Based on morphological and molecular phylogenetic evidence, our results explicitly indicated that should be a member of , rather than , and is a distinct species closely related to , and . Thus, the new combination (B.
View Article and Find Full Text PDFAdverse outcome pathway (AOP)-based computational models provide state-of-the-art prediction for human skin sensitizers and are promising alternatives to animal testing. However, little is known about their applicability to pesticides due to scarce pesticide data for evaluation. Moreover, pesticides traditionally have been tested on animals without human data, making validation difficult.
View Article and Find Full Text PDFFunctional diversity is an integrative approach to better understand biodiversity across space and time. In the present study, we investigated the spatiotemporal patterns (i.e.
View Article and Find Full Text PDFExploring species richness patterns across space and time can help in understanding species distribution and in formulating conservation strategies. Among taxa, amphibians are of utmost importance as they are highly sensitive to environmental changes due to their unique life histories (Zhong et al., 2018).
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