Publications by authors named "Chun-Kai Oscar Chang"
Article Synopsis
- A study compared the hypersensitivity reactions of a new dermal filler (test filler) made with a novel cross-linking technology to a traditional filler (control filler) for correcting nasolabial folds.
- Participants (n = 279) underwent a screening allergy test with intradermal injections, where the test filler showed no allergic reactions (0%) while the control filler had a small percentage (1.5%).
- Overall, the test filler had fewer hypersensitivity reactions, no serious adverse events related to its use, and most side effects were common and resolved within a year, supporting its safe application without skin testing beforehand.
Purpose: Porcine-based dermal injectable collagen is effective for nasolabial fold correction. In the present study, a new dermal injectable collagen, incorporating a novel cross-linking technology and premixed with lidocaine, was introduced. The study aimed to determine the efficacy of the new dermal injectable collagen in improving bilateral nasolabial fold wrinkles, and reducing pain during injection.
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