Publications by authors named "Chun-Hsien Yen"
The administration of zoledronic acid (ZA) to patients who received cementless total hip arthroplasty (THA) has been reported to reduce bone turnover markers (BTMs) and increase bone mineral density (BMD). The effects of two-dose ZA versus placebo on cementless THA patients were analyzed in this five-year extension study. Alkaline phosphatase (ALP), osteocalcin (OC), procollagen 1 intact N-terminal propeptide (P1NP), serum calcium, renal function, radiological findings, and functional outcomes were compared in 49 patients, and the periprosthetic BMD of seven Gruen zones were compared in 19 patients.
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- Portal hypertension is a serious condition that arises from liver cirrhosis, leading to complications and portal-systemic collaterals.
- A study investigated the effects of glycyrrhizin, an anti-angiogenic compound, on cirrhotic rats with portal hypertension induced by bile duct ligation.
- Results showed that glycyrrhizin significantly lowered portal pressure and reduced collateral shunting, hinting at its potential to suppress mesenteric angiogenesis without greatly affecting liver biochemistry.