Identification of chemosensitizing agents of colorectal cancer in using an NMR-based chemometric approach.

Searching for new adjuvants of conventional chemotherapeutic approaches against colorectal cancer cells is extremely urgent. In current research, a non-targeted analytical approach was established by combining proton nuclear magnetic resonance spectroscopy with a chemometrics data mining tool to identify chemosensitizing agents from . This approach enabled the identification of potential active constituents in the initial fractionation process and provided their structural information.