Polyethyleneimine-assisted co-deposition of polydopamine coating with enhanced stability and efficient secondary modification.

The stability and grafting efficiency are important for polydopamine (pDA) coatings used as platforms for secondary grafting. In this work, polyethyleneimine (PEI) was co-deposited with dopamine on various materials (PP, PTFE and PVC), then immersed in a 1.0 M HCl solution or 1.

Study of the microstructure of chitosan aerogel beads prepared by supercritical CO drying and the effect of long-term storage.

In order to investigate the pore properties and effect of storage time on the microstructure of CO-dried aerogels, chitosan aerogel beads were obtained from chitosan hydrogels with an initial concentration in the range of 1.5-3.0 wt% through SCCO drying and freeze-drying (as a comparison).

Heparin as a molecular spacer immobilized on microspheres to improve blood compatibility in hemoperfusion.

Heparin, a highly sulfated linear polysaccharide, with anticoagulation function and blood compatibility is widely used as a biomaterials in medical application, but the most importance of heparin is its structure function as the macromolecular space arm. In this study, heparin as a spacer was covalently immobilized on the chloromethylated polystyrene microspheres (Ps) and then connected with l-phenylalanine forming the Ps-Hep-Phe structure, which was developed for endotoxin adsorption in hemoperfusion. The grafting density of heparin reach the maximum when the initial concentration of heparin solution was 5 mg/mL.