Publications by authors named "Chun-Chun Du"
Article Synopsis
- - The study discovered 12 new compounds called filicinic acid-based meroterpenoids (1-12) from Hypericum elodeoides, characterized by their unique ring structures identified using advanced spectroscopic techniques and molecular calculations.
- - Biological tests indicated that compounds 1a, 5a, and 11b can activate a specific receptor (RXRα) and increase the expression of a protein (ABCA1) that is involved in cholesterol transport.
- - Among these, compound 1a showed a strong potential for treating Alzheimer's disease by promoting the clearance of β-amyloid plaques through its interaction with RXRα, as supported by various assays including molecular docking studies.
(±)-Hypersines A-C (-), the three pairs of enantiomerically pure monoterpenoid polyprenylated acylphloroglucinols with an unprecedented 6/6/5/4 fused ring system, were isolated from . Their structures, including absolute configurations, were elucidated by comprehensive spectroscopic data, single-crystal X-ray diffraction, and quantum chemical calculations. The plausible, biosynthetic pathway of - was proposed.
View Article and Find Full Text PDF