Development and validation of an immune-related prognosis signature associated with hypoxia and ferroptosis in hepatocellular carcinoma.

Background: Hypoxia and ferroptosis are crucial in the occurrence and development of hepatocellular carcinoma (HCC), and they both affect the immune status of the tumor microenvironment. Previous studies have also shown a link between hypoxia and ferroptosis.

Patients And Methods: In all, 814 HCC cases from The Cancer Genome Atlas and Gene Expression Omnibus databases were used as the discovery cohort, and 230 HCC cases from the International Cancer Genome Consortium database were used as the validation cohort.

[Qinghuachang Decoction Inhibited NF-kappaB Activation in LPS-induced Human Enterocytes].

Objective: To explore anti-inflammation and mechanism of Qinghuachang Decoction (QD) by using LPS stimulated differentiated colon cancer Caco-2 cells (as an inflammation model of human enterocytes).

Methods: QD was prepared. Human colonic epithelial Caco-2 cells were cultured.

A Novel Molecular Cytogenetic Finding of Leiomyomatosis Peritonealis Disseminata.

Background: Leiomyomatosis peritonealis disseminata (LPD) is a rare disease characterised by the subperitoneal proliferation of smooth muscle cells that form benign nodules. A few studies have aimed to reveal the pathogenesis of LPD without reaching a clear explanation.

Methods: Karyotype analysis and array-comparative genomic hybridization (aCGH) of a human LPD case were performed to evaluate the role of chromosomal abnormalities in LPD pathogenesis.

[Forensic identification by coding of frontal sinus characteristics of CT].

Objective: To explore observing parameters of frontal sinus using reconstructive coronal nose bone sections of the head CT images and to establish the special identification codes.

Methods: CT images of the frontal sinus were analyzed by using distance measurement and morphological description. The discrimination codes of frontal sinus identification were: the number of right partial septa, shape-the location of the central septa, shape-the number of left partial septa, shape; the number of arches of right upper scalloping (the location of the right highest scalloping, the location of the right lowest scalloping)-the number of arches of left upper scalloping (the location of the left highest scalloping, the location of the left lowest scalloping); the width, height of the right sinus-the total width of sinus-the width, height of the left sinus.

[Influence of Xianglingwan on dysmenorrhea and serum CA125 in treating patients with endometriosis].

Objective: To observe the influence of Xianglingwan on dysmenorrhea and serum CA125 in treating patients with endometriosis.

Method: A total of 54 patients with endometriosis and without medical complications were random selected. Xianglingwan was administered from the fifth day of the menstrual cycle for 3 weeks every month as a therapeutic course, and three months for a therapeutic period.