Publications by authors named "Chun Yin See"
Background: Glucagon-like Peptide-1 Receptor Agonists (GLP-1RAs) have demonstrated efficacy in improving mortality and cardiovascular (CV) outcomes. However, the impact of GLP-1RAs therapy on cardiorenal outcomes of diabetic patients at the commencement of dialysis remains unexplored.
Purpose: This study aimed to investigate the long-term benefits of GLP-1RAs in type 2 diabetic patients at dialysis commencement.
Importance: The interplay among baseline kidney function, severity of acute kidney disease (AKD), and post-AKD kidney function has significant associations with patient outcomes. However, a comprehensive understanding of how these factors are collectively associated with mortality, major adverse cardiac events (MACEs), and end-stage kidney disease (ESKD) in patients with dialysis-requiring acute kidney injury (AKI-D) is yet to be fully explored.
Objective: To investigate the associations of baseline kidney function, AKD severity, and post-AKD kidney function with mortality, MACEs, and ESKD in patients with AKI-D.
Impact of SGLT2 inhibitors on patient outcomes: a network meta-analysis.
Cardiovasc Diabetol
October 2023
Article Synopsis
- - A comprehensive network meta-analysis was performed on SGLT2 inhibitors, analyzing data from 14 trials with over 75,000 patients, aiming to compare their effectiveness in populations with and without conditions like diabetes, heart failure, and chronic kidney disease.
- - Key findings showed that empagliflozin users had a significantly lower all-cause mortality risk compared to dapagliflozin users in the diabetic population, while canagliflozin users had a reduced risk of cardiovascular death or hospitalization in non-heart failure patients compared to dapagliflozin users.
- - The analysis also indicated that less selective SGLT2 inhibitors led to significantly lower risks of major adverse cardiovascular events in heart failure patients compared to highly
Introduction: Various approaches have been suggested to identify acute kidney injury (AKI) early and to initiate kidney-protective measures in patients at risk or with AKI. The objective of this study was to evaluate whether care bundles improve kidney outcomes in these patients.
Methods: We conducted a systematic review of the literature to evaluate the clinical effectiveness of AKI care bundles with or without urinary biomarkers in the recognition and management of AKI.
Blood pressure (BP) variation may result in poor cardiovascular and renal outcomes. We investigated the pattern of seasonal BP change and its association with outcomes in patients with chronic kidney disease (CKD) living in southern Taiwan. We conducted a retrospective analysis of a prospective observational cohort consisting of outpatients with CKD for the period between December 2014 and December 2019.
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