Side-chain conformations in the isomorphous polyfluorinated {4,4'-bis[(2,2-difluoroethoxy)methyl]-2,2'-bipyridine-κN,N'}dichloridopalladium and -platinum complexes.

The polyfluorinated title compounds, [MCl(CHFNO)] or [4,4'-(HCFCHOCH)-2,2'-bpy]MCl [M = Pd, (1), and M = Pt, (2)], have -C(H)OC(H)CFH side chains with H-atom donors at the α and β sites. The structures of (1) and (2) are isomorphous, with the nearly planar (bpy)MCl molecules stacked in columns. Within one column, π-dimer pairs alternate between a π-dimer pair reinforced with C-H.

Government-funded universal newborn hearing screening and genetic analyses of deafness predisposing genes in Taiwan.

Objective: To investigate the association of eight connexin genes (GJB2, GJB4, GJA1P1, GJB6, GJB3, GJA1, GJB1, and GJC3) and the SLC26A4 gene with congenital hearing impairment among infants in a universal newborn hearing screening program.

Method: From September 2009 to October 2013, the consecutive neonates born in all six branches of Taipei City Hospital were enrolled. Infants who failed the newborn hearing screening and were diagnosed with hearing impairment underwent the genetic analyses.