Publications by authors named "Chun Te Wu"
Background: Evaluating risk factors for bleeding events in robot-assisted partial nephrectomy (RAPN) for renal angiomyolipoma (RAML) is essential for improving surgical outcomes.
Methods: We performed a retrospective analysis of patients who underwent RAPN for renal masses between May 2019 and June 2023 at a single medical center, categorizing them into AML and non-AML groups. We assessed demographic data, perioperative complications, and postoperative outcomes.
Objective: To investigate the impact of body mass index (BMI) on preoperative characteristics, lower urinary tract symptoms (LUTS), intraoperative variables, surgical outcomes and postoperative complications.
Methods: This is a retrospective observational study including 891 benign prostate hyperplasia (BPH) patients who underwent GreenLight Laser photoselective vaporization of the prostate (PVP) between 2014 and 2020. Clinical characteristics, uroflowmetry parameters, and surgery related parameters were extracted from electronic health records.
Article Synopsis
- * Out of 16,160 spinal surgery patients analyzed, 432 (2.67%) experienced APOUR, with significant risk factors identified as being older, male, and having undergone more than two spinal surgeries.
- * The findings suggest that understanding these risk factors may help surgeons identify high-risk patients and provide earlier interventions to improve postoperative outcomes.
Background: This study aimed to identify the clinical predictors for the response of patients with mCRPC to ARATs.
Materials And Methods: We retrospectively collected data on consecutive patients who were diagnosed with mCRPC and underwent ARAT treatment during this stage of the disease. Clinical parameters were obtained through medical chart reviews.
Article Synopsis
- The study focused on evaluating clinically significant outcome (CSO) thresholds for patient-reported functional scores following rotator cuff surgeries, specifically comparing cases with and without long head of the biceps tendon (LHBT) augmentation.
- A total of 43 patients who underwent arthroscopic superior capsular reconstruction (SCR) were analyzed based on various patient-reported outcome measures (PROMs) and radiographic data collected between 2016 and 2020.
- Results indicated differences in patient satisfaction and perceived improvement, with significant functional score differences favoring those who were satisfied; however, there was no notable difference in pain scores between the two groups.
Article Synopsis
- This study developed a new model that merges clinical data and imaging results to more accurately predict early recovery from urinary incontinence following robotic-assisted radical prostatectomy (RARP).
- Researchers analyzed data from 293 patients, finding that 47.6% were pad-free within a month, with over 90% achieving continence by six months.
- Significant predictors for recovery included BMI, nerve-sparing techniques, and bladder neck positioning, leading to the creation of a nomogram to help clinicians manage patient care and alleviate concerns.
MRI-guided targeted biopsy (MRGB) was recommended as part of biopsy paradigm of prostate cancers by current guidelines. This study aimed to analyze the diagnostic efficacy of MRGB and systemic biopsy (SB), and to compare diagnostic capabilities within subgroups of MRGB: MRI-cognitive biopsy (MRCB) and MRI-fusion biopsy (MRFB). We retrospectively enrolled patients who underwent MRGB for suspicious malignant lesion(s) identified on MRI in a single tertiary center, sample size was 74 patients.
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- The study aimed to evaluate the reliability and validity of the Traditional Chinese version of the Cancer Survivors' Self-Efficacy Scale (CS-SES-TC) among 300 genitourinary cancer survivors in Taiwan.
- Results from confirmatory factor analysis (CFA) confirmed that the CS-SES-TC is a unidimensional scale and showed strong psychometric properties, including high factor loadings (above 0.6) and good goodness-of-fit metrics.
- The scale demonstrated concurrent and discriminant validity, along with a high reliability score (Cronbach's α between .97 and .98), making it a useful tool for healthcare providers to assess cancer survivors' self-efficacy.
Article Synopsis
- * This study explored the link between pelvic adipose tissue (fat) and the severity of PCa by analyzing tissue samples from 50 patients who underwent prostate surgery, examining the impact of periprostatic adipose tissue (PPAT) on cancer cell behavior.
- * Findings showed that higher levels of PPAT and pelvic fat correlated with worse PCa aggressiveness and that PPAT-conditioned medium reduced the growth of certain PCa cell lines, highlighting the potential role of fat tissue in modulating cancer behavior
Article Synopsis
- - Our study investigates how Galectin-1 (Gal-1) contributes to the immunosuppressive environment in prostate cancer (PCa), finding that higher levels of Gal-1 are linked to more advanced cancer stages and can lead to T cell death.
- - We discovered that PCa cells can secrete Gal-1, which decreases T cell infiltration and activity, but blocking Gal-1 with a treatment called LLS30 can reverse this effect and boost T cell presence in tumors.
- - Additionally, LLS30 not only prevents T cell apoptosis by disrupting Gal-1's interactions but also shows potential to improve the effectiveness of anti-PD-1 therapies, suggesting that targeting Gal-1 could enhance immunotherapy strategies
Article Synopsis
- A study was conducted to evaluate early continence outcomes after a specific surgical technique (three-layer vesicourethral reconstruction) during robot-assisted radical prostatectomy (RARP) in 170 prostate cancer patients.
- Results showed that patients who underwent the three-layer reconstruction had significantly better continence rates at various postoperative intervals compared to those who had a one-layer reconstruction, with a 42% lower risk of incontinence.
- Postoperative cystography results indicated that the three-layer group experienced less leakage and better bladder neck positioning, which contributed to overall improved continence outcomes.
Article Synopsis
- This study evaluated the outcomes of bladder-preservation strategies using maximal transurethral resection of bladder tumors (TURBT) combined with either pembrolizumab or chemotherapy in patients with muscle-invasive bladder cancer (MIBC) who opted against radical treatment.
- A total of 53 patients were analyzed, and 43.4% achieved clinical complete response after treatment, with slightly better results in the pembrolizumab group compared to chemotherapy.
- The study found that patients receiving pembrolizumab had longer progression-free survival (PFS) and overall survival (OS) compared to those receiving chemotherapy, highlighting the potential of bladder preservation as a viable treatment option for selected MIBC patients.
Article Synopsis
- * Researchers used both cross-sectional and longitudinal methods, collecting data from patients at two hospitals in Taiwan between August 2017 and December 2020, including responses from 177 patients and 34 newly diagnosed patients at various points during treatment.
- * Results indicated that dissatisfaction with BI varied between 6.1% and 17.2%, with hormonal symptoms correlating with this dissatisfaction, suggesting the need for education on HT side effects and coping strategies to enhance patients’ BI.
Article Synopsis
- The study assessed the feasibility and efficacy of a multimedia-based hormone therapy information program (HTIP) for prostate cancer patients receiving hormone therapy.
- Patients were randomly divided into a multimedia information group and a control group, with the multimedia group receiving weekly sessions for 6 weeks.
- Preliminary results indicated high patient satisfaction and improved positive thinking and quality of life in the multimedia group, although these improvements were not statistically significant, suggesting the need for further research with larger sample sizes.
Article Synopsis
- Urinary incontinence is a frequent issue for prostate cancer patients post-surgery, prompting the creation of a self-management intervention to help them cope.
- The intervention includes a mobile app, a handbook, and professional support, designed to be assessed for feasibility, acceptability, and effectiveness through a controlled study.
- Participants will be randomly assigned to either the self-management program or a control group receiving minimal dietary education, with their progress tracked over a 12 to 16-week period.