Topical halometasone cream combined with fire needle pre-treatment for treatment of primary cutaneous amyloidosis: Two case reports.

Background: Primary cutaneous amyloidosis (PCA) is a chronic metabolic skin disease that has a detrimental impact on physical and mental health. It appears as mossy papules and severe itching, which is long-term and recurrent. Traditional treatments are unsatisfactory, especially for refractory cases.

Effective Treatment of Small Uncomplicated Skin Abscesses with Fire Needle: A Case Series.

Background: Uncomplicated skin abscesses are collections of pus within the skin structure and are usually caused by bacterial infections. Clinically, they are quite common and inevitably affect people of any age. The current management strategies comprise prompt initiation of antibiotics and incision and drainage.

FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.

Background: Non-small cell lung cancer (NSCLC) accounts for more than 80% of the total lung cancer and gemcitabine (GEM)-based chemotherapy is the first-line therapeutic approach for NSCLC treatment. Owing to acquired chemo-resistance, the prognosis of NSCLC patients receiving GEM treatment is still poor.

Methods: Dysregulation of mRNAs in GEM-resistant (GR) NSCLC cells comparing to parental cells were profiled by analyzing GSEA6914 datasets from GEO database.

AlGaN/GaN MISHEMTs with AlN gate dielectric grown by thermal ALD technique.

Recently, AlN plasma-enhanced atomic layer deposition (ALD) passivation technique had been proposed and investigated for suppressing the dynamic on-resistance degradation behavior of high-electron-mobility transistors (HEMTs). In this paper, a novel gate dielectric and passivation technique for GaN-on-Si AlGaN/GaN metal-insulator-semiconductor high-electron-mobility transistors (MISHEMTs) is presented. This technique features the AlN thin film grown by thermal ALD at 400°C without plasma enhancement.

Fas/FasL pathway-mediated alveolar macrophage apoptosis involved in human silicosis.

In vitro and in vivo studies have demonstrated that lung cell apoptosis is associated with lung fibrosis; however the relationship between apoptosis of alveolar macrophages (AMs) and human silicosis has not been addressed. In the present study, AM apoptosis was determined in whole-lung lavage fluid from 48 male silicosis patients, 13 male observers, and 13 male healthy volunteers. The relationships between apoptosis index (AI) and silica exposure history, soluble Fas (sFas)/membrane-bound Fas (mFas), and caspase-3/caspase-8 were analyzed.

The tempo-spatially modulated polarization atmosphere Michelson interferometer.

A space-based tempo-spatially modulated polarization atmosphere Michelson interferometer (TSMPAMI) is described. It uses the relative movement between the TSMPAMI and the measured target to change optical path difference. The acquisition method of interferogram is presented.

[Challenge to the desertification reversion in Horqin Sandy Land].

Analyses of the changes in desertified land area, water resource availability, land use, and plant productivity in Horqin Sandy Land in recent 50 years showed that from 1950 to the late 1980s, the land desertification in Horqin Sandy Land had a rapid expansion, but reversed since then. The annual runoff of Xiliaohe River decreased consistently, and in 1999, the middle reach at Tongliao section was dried up. In recent 20 years, the water table of Xihu Lake was decreased by about 10 m, and dried up in 2001.

[Protective effects of continue insulin infusion on liver mitochondrion in the early stage of septic rats].

Aim: To investigate the protective effects of continue insulin infusion on liver mitochondrion and its mechanism in the early stage of lipopolysaccharide-induced septic rats.

Methods: 24 SD rats were randomly divided into 3 groups (An external jugular vein catheterization was performed in every rat a day before intraperitoneal injection): Saline control group (n = 8), LPS group (n = 8) and insulin therapy group (n = 8). Saline control group animals received 9 g/L saline only.

[Effect of fumigation therapy with yinxieling on T-bet and GATA-3 protein expression in the peripheral blood monocyte of patients with psoriasis vulgaris].

Objective: To evaluate the effect of fumigating with Yinxieling (YXL) in treating patients with psoriasis vulgaris and its influence on T-bet and GATA-3 protein expressions in peripheral blood monocyte (PBMC).

Methods: Western blot method was employed to detect the T-bet and GATA-3 protein expressions in PBMC of 30 psoriasis vulgaris patients before and after they received fumigation therapy with YXL, also in 25 healthy persons for controls. The therapeutic efficacy was observed and the relationship between PASI scores and levels of T-bet and GATA-3 analyzed.

[Clinical study on treatment of atopic dermatitis by integrated traditional Chinese and Western medicine].

Objective: To observe the clinical effects and explore the mechanism of the integrated traditional Chinese and Western medicine in treating atopic dermatitis (AD).

Methods: Forty-seven patients with AD were randomly assigned to two groups, the control group and the treated group, they were treated with conventional Western medicine (10 mg Loratadine tablet, once daily) and with integrated medicine additionally given modified Jiawei Danggui Decection besides Western medicine respectively for 4 weeks. Double-sandwich ELISA was used to detect the levels of interleukin- 4, -10 and -12 (IL-4, IL-10 and IL-12) before and after treatment.

[Research on theory and application of the interferogram of Voigt profile].

At normal pressure, Voigt profile (the convolution of Gaussian profile and Lorentzian profile) is the closest to actual profile, but it has no accurate expression, so in actual application many approximations are used to express Voigt profile. In the present paper, without any approximation, the authors calculate the interferogram of Voigt profile, showing that Voigt profile has no expression, but its interferogram can be calculated strictly. The transform has only one term, which is very similar to the expressions of Gaussian profile and Lorentzian profile, so any calculations of the widened profile can be finished, which doesn't have two terms as some papers predict, and difficulties will be brought.

[Effects of neuropeptide Y on ion channels in ventricular myocytes].

Neuropeptide Y (NPY) co-exists with norepinephrine (NE) in sympathetic terminals, and is the most abundant neuropeptide in myocardium. Many studies have focused on the effects of NE on ion channels in cardiac myocytes and its physiological significance has been elucidated relatively profoundly. There have been few investigations, however, on the physiological significance of NPY in myocardium.