Predictive factors for coronal and sagittal graft extrusion length after using tendon autograft for medial meniscus reconstruction.

Background: Meniscus extrusion occurs in most elderly individuals and most patients after meniscus allograft transplantation. The risk factors and correlative factors of meniscus extrusion have been extensively studied. However, for using tendon autograft for meniscus reconstruction, both graft type and surgical method are different from those in previous studies on meniscus extrusion.

Increased serum asprosin is correlated with diabetes mellitus-induced erectile dysfunction.

Objective: Asprosin, a newly identified adipokine, is pathologically increased in type 2 diabetes. The aim of this study is to see whether serum asprosin concentrations are linked to diabetes mellitus-induced erectile dysfunction (DMED).

Methods: 90 male patients with type 2 diabetes were included.

Forest fire risk zoning based on fuzzy logic and analytical network process.

Forest fires have a significant impact on human life, property safety, and ecological environment. Deve-loping high-quality forest fire risk maps is beneficial for preventing forest fires, guiding resource allocation for firefighting, assisting in fire suppression efforts, and supporting decision-making. With a multi-criteria decision analysis (MCDA) method based on geographic information systems (GIS) and literature review, we assessed the main factors influencing the occurrences of forest fires in Youxi County, Fujian Province.

The role of early cerebral edema and hematoma assessment in aneurysmal subarachnoid hemorrhage (a-SAH) in predicting early brain injury (EBI) and cognitive impairment: a case controlled study.

Background: Early assessment and management of cerebral edema and hematoma following aneurysmal subarachnoid hemorrhage (a-SAH) can significantly impact clinical cognitive outcomes. However, current clinical practices lack predictive models to identify early structural brain abnormalities affecting cognition. To address this gap, the authors propose the development of a predictive model termed the a-SAH Early Brain Edema/Hematoma Compression Neural (Structural Brain) Networks Score System (SEBE-HCNNSS).

PKM2 is a Novel Osteoporosis-Associated Protein in Chinese.

Unlabelled:                        Purpose:Osteoporosis is characterized by low bone mineral density (BMD) and high risk of osteoporotic fracture (OF). Peripheral blood monocytes (PBM) can differentiate into osteoclasts to resorb bone. This study was to identify PBM-expressed proteins significant for osteoporosis in Chinese Han elderly population (>65 years), and focused on two phenotypes of osteoporosis: low BMD and OF.

Tracking the temporal dynamics of the face-like inversion effect as revealed by Chinese characters using magnetoencephalography.

The neural basis of configural processing has been extensively studied by exploiting face inversion during recognition, and growing evidence has revealed that word inversion also involves changes in configuration. However, the neural dynamics of face-like inversion effects remain unclear. Here, we tracked the temporal dynamics of neural responses that were sensitive to inversion during Chinese character recognition as they occurred during face recognition using multivariate decoding and temporal generalization analyses.

The diagnostic significance of cerebrospinal fluid cytology and circulating tumor DNA in meningeal carcinomatosis.

Objective: The objective of this research is to investigate the clinical application value of cerebrospinal fluid (CSF) cytology and circulating tumor DNA (ctDNA) in lung adenocarcinoma (LUAD) meningeal metastasis-meningeal carcinomatosis (MC), and to further explore the possible molecular mechanisms and drug treatment targets of LUAD meningeal metastasis by next-generation sequencing (NGS).

Methods: We retrospectively analyzed LUAD with MC in 52 patients. CSF cytology was carried out using the slide centrifugation precipitation method and May-Grüwald-Giemsa (MGG) staining.

Pore Environment Optimization of Microporous Metal-Organic Frameworks with Huddled Pyrazine Pillars for CH/CO Separation.

Metal-organic frameworks (MOFs) have been proven promising in addressing many critical issues related to gas separation and purification. However, it remains a great challenge to optimize the pore environment of MOFs for purification of specific gas mixtures. Herein, we report the rational construction of three isostructural microporous MOFs with the 4,4',4"-tricarboxyltriphenylamine (HTCA) ligand, unusual hexaprismane NiO cluster, and functionalized pyrazine pillars [PYZ-x, x = -H (DZU-10), -NH (DZU-11), and -OH (DZU-12)], where the building blocks of NiO clusters and huddled pyrazine pillars are reported in porous MOFs for the first time.

Temporal expectation based on the duration variability modulates alpha oscillations during working memory retention.

While maintaining information over a delay of time, working memory (WM) also allows individuals to prepare the mnemonic contents for prospective utilisation. However, it remains unclear whether the expectation of the time of WM test could modulate neural responses during the retention interval of WM and subsequent performance. Here, we investigated whether temporal expectations based on the variability of delay duration can modulate 9-13 Hz alpha oscillations during WM retention and whether the expectation-induced alpha activity was associated with WM performance.

A Practical Assessment of the Disinfectant Efficacy of UV Light with and without Ozone Using a Novel Transfer Hatch in a Research Animal Facility.

Most in vivo animal research and breeding using mice and rats in China takes place in facilities under barrier conditions. Items being moved across the barrier are typically disinfected using UV radiation in a transfer hatch. However, the time periods necessary for this disinfection technique are inefficient, and disinfection is frequently incomplete, especially if concealed surfaces are present.

A (3,8)-Connected Metal-Organic Framework with Bending Dicarboxylate Linkers for CH/CO Separation.

Herein, by replacement of the linear terephthalate linker with the bending 2,5-thiophenedicarboxylate (tdc) linker in the typical (3,9)-connected metal-organic framework, with a reduced 8-connected hydroxyl-centered trinuclear cluster, a new (3,8)-connected network, [Ni(μ-OH)(tdc)(tpp)] [; tpp = 2,4,6-tris(4-pyridyl)pyridine], was synthesized. The modified pore environment enables to selectively adsorb CH over CO in an efficient manner.

Spermatocytic tumor: A rare case report.

Background: Spermatocytic tumor is a rare, malignant neoplasm of the testes. Since the prognosis for this tumor type is favorable, accurate diagnosis and differentiation from other malignant testicular neoplasms (classic seminoma and lymphoma) are crucial. To add to the existing literature on the diagnosis of spermatocytic tumor, herein we report the detailed clinical and histopathologic findings for a case that we encountered.

The effects of stimulus inversion on the neural representations of Chinese character and face recognition.

This study investigates whether stimulus inversion influences neural responses of Chinese character recognition similarly to its effect on face recognition in category-selective and object-related brain areas using functional magnetic resonance imaging. Participants performed a one-back matching task for simple (one radical) and compound (two radicals) Chinese characters and faces with upright and inverted orientations. Inverted stimuli produced slower response times with stronger activity within the fusiform gyrus (FG) than upright stimuli for faces and Chinese characters.

Collision carcinoma of the rectum involving neuroendocrine carcinoma and adenocarcinoma: A case report.

Background: Collision carcinoma is a rare histological pattern, and includes two or more different types of tumors coexisting in the same organ as one neoplasm. Different to the combined type, the two adjacent tumors of collision carcinoma are histologically distinct. Collision carcinoma may occur from any origin or organ, including the cecum, liver, cervix, thyroid, stomach, kidney, and esophagus.

[microRNA-1 gene delivery mediated by exosomes suppresses CAL-27 cell proliferation].

Objectives: This study aims to construct endogenous exosomes abundantly loaded with miR-1 and investigate the role of exosome-mediated microRNA-1 (miR-1) delivery on CAL-27 cell proliferation.

Methods: Exosomes secreted by miR-1-overexpressing HEK293 cells (miR1-EXO) were purified via ultracentrifugation and subjected to transmission electron microscopy, nanoparticle analysis, Western blot analysis, and quantitative polymerase chain reaction (qPCR). CAL-27 cells were cocultured with exosomes secreted by HEK293 cells (CON-EXO) and miR1-EXO and equivalent phosphate buffer saline.

4-Methoxydalbergione is a potent inhibitor of human astroglioma U87 cells in vitro and in vivo.

Astroglioma is the most common primary tumor in the central nervous system without effective treatment strategies. Temozolomide (TMZ) is a chemotherapeutic drug to treat astroglioma but exhibits low potency and has side effects. Therefore, there is an urgent need to develop new compounds to treat astroglioma.

ANP reduced Hedgehog signaling-mediated activation of matrix metalloproteinase-9 in gastric cancer cell line MGC-803.

Objective: Gastric cancer is the most common malignant tumor. Most patients suffering from gastric cancer die of metastasis. The role of Atrial natriuretic peptide (ANP) in inhibiting and eliminating kinds of cancer cells has been reported.

Ultrastructure of gap junction and Cx43 expression in gastric cancer tissues of the patients.

Introduction: Gap junctions are intercellular channels formed by connexin facilitating communication between cells by allowing transfer of ions and small signaling molecules. Connexin 43 (Cx43) is the most ubiquitous connexin in human tissues. Ample evidence suggests the role of gap junction and its connexins such as connexin 43 in human cancers including gastric cancer, which has an important place in the worldwide incidence of cancer and cancer-related deaths.

The urinary levels of CTX-II, C2C, PYD, and Helix-II increased among adults with KBD: a cross-sectional study.

Background: Kashin-Beck disease (KBD) is an endemic osteoarthropathy, and its pathogenesis is still not entirely clear. Pathologically, many KBD changes are similar to those of osteoarthritis (OA). Therefore, this study aimed to identify changes in the levels of potential urinary biomarkers for OA, including C-telopeptide of type II collagen (uCTX-II), type II collagen cleavage neoepitope (uC2C), pyridinoline (uPYD), and uHelix-II, among adults with KBD.

Abl interactor 1: A novel biomarker for osteoporosis in Chinese elderly men.

Low bone mineral density (BMD) is a high-risk factor of osteoporosis (OP) and osteoporotic fracture (OF). Peripheral blood monocytes (PBM) can give birth to osteoclasts to resorb bone. Herein, we attempted to identify OP susceptible proteins in human PBM and characterize their functions in bone.

[Effects of Flooding and Drying on the Transformation of Soil Inorganic Phosphorus in the Water-Level-Fluctuating Zone of the Three Gorges Reservoir, China].

The implementation of the Three Gorges Project formed a water-level-fluctuating zone, and flooding and drying affects the soil properties and water quality of the Water-Level-Fluctuating Zone. The laboratory simulation or field sampling were conducted; however, the results cannot reflect the real conditions in practice. The effects of flooding and drying on the physical and chemical properties of soil and the transformation characteristics of inorganic phosphorus were studied in order to provide a theoretical reference for soil phosphorus loss and water eutrophication in water-level-fluctuating zone of the Three Gorges Reservoir.

Top-down modulation of alpha power and pattern similarity for threatening representations in visual short-term memory.

Recent studies have shown that top-down attention biases task-relevant representations in visual short-term memory (VSTM). Accumulating evidence has also revealed the modulatory effects of emotional arousal on attentional processing. However, it remains unclear how top-down attention interacts with emotional memoranda in VSTM.

Predictive Value of Cumulative Blood Pressure for All-Cause Mortality and Cardiovascular Events.

The predictive value of cumulative blood pressure (BP) on all-cause mortality and cardiovascular and cerebrovascular events (CCE) has hardly been studied. In this prospective cohort study including 52,385 participants from the Kailuan Group who attended three medical examinations and without CCE, the impact of cumulative systolic BP (cumSBP) and cumulative diastolic BP (cumDBP) on all-cause mortality and CCEs was investigated. For the study population, the mean (standard deviation) age was 48.