Publications by authors named "Chun Him Hui"

CoronaVac immunogenicity decreases with time, and we aimed to investigate whether gut microbiota associate with longer-term immunogenicity of CoronaVac. This was a prospective cohort study recruiting two-dose CoronaVac recipients from three centres in Hong Kong. We collected blood samples at baseline and day 180 after the first dose and used chemiluminescence immunoassay to test for neutralizing antibodies (NAbs) against the receptor-binding domain (RBD) of wild-type SARS-CoV-2 virus.

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Background And Objective: Recent advances have led to cure or long-term disease control for patients with hematological malignancy (HM). Unfortunately, some of them still have poor prognoses and are often associated with significant symptom burden and poor quality of life for patients and families. These patients usually require supportive care including red blood cell and platelet transfusion, due to disease itself and the oncological treatment, apart from their symptom management.

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Gut microbiota can be associated with COVID-19 vaccine immunogenicity. We investigated whether recent antibiotic use influences BNT162b2 vaccine immunogenicity. BNT162b2 recipients from three centers were prospectively recruited.

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Article Synopsis
  • Early palliative care (EIPC) has been shown to improve clinical outcomes for patients with advanced medical illnesses, but most studies have not focused on those with advanced hematologic cancer (HC), which often presents substantial physical and psychological symptoms.
  • An EIPC collaboration in Hong Kong began in 2018 between Queen Mary Hospital and Grantham Hospital, aiming to better address the needs of HC patients who have failed multiple cancer treatments, through a structured multidisciplinary approach involving hematologists, palliative care physicians, and clinical psychologists.
  • A retrospective study from June 2018 to September 2020 included 38 patients who underwent assessments; findings revealed that a significant portion experienced symptoms like fatigue, anxiety, and depression, highlighting the need for integrated
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Patients with asthma were advised to avoid coronavirus disease (COVID-19) and comply with medication during the COVID-19 pandemic. Respiratory tract infection is a common cause of asthma exacerbations. There has not been evidence suggesting the link between COVID-19 and asthma exacerbation, especially in places with dramatic responses in infection control with universal masking and aggressive social distancing.

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