AflaILVB/G/I and AflaILVD are involved in mycelial production, aflatoxin biosynthesis, and fungal virulence in .

Aflatoxins (AFs) are produced by fungi such as and and are one of the most toxic mycotoxins found in agricultural products and food. Aflatoxin contamination, which requires the control of , remains problematic because of the lack of effective strategies and the exploration of new compounds that can inhibit growth and mycotoxin production is urgently required to alleviate potential deleterious effects. Acetohydroxy acid synthase (AHAS) and dihydroxy acid dehydratase are important enzymes in the biosynthetic pathways of branched-chain amino acids (BCAAs), including isoleucine, leucine, and valine.

Transcriptomic and Proteomic Insights into the Effect of Sterigmatocystin on .

is an important fungus that produces aflatoxins, among which aflatoxin B (AFB) is the most toxic and contaminates food and poses a high risk to human health. AFB interacts with another mycotoxin sterigmatocystin (STC), which is also a precursor of AFB. Herein, we determined the effect of STC on AFB by evaluating transcriptomic and proteomic profiles in the presence or absence of STC by RNA-seq and isobaric tagging, respectively.

The Impact of Stigmatization on Social Avoidance and Fear of Disclosure among Older People: Implications for Social Policy Preparedness in a Public Health Crisis.

This study examined whether older people with epicenter travel experiences in the event of the novel coronavirus disease epidemic suffered from stigmatization, which in turn affected subsequent behavior, including fear of disclosure and social avoidance. A three-wave survey was conducted using a time-lagged design of older people who had travel experiences in Hubei, China on the eve of the outbreak. Results reveal positive associations between stigmatization and stress, social avoidance, and fear of disclosure, in addition to positive associations between stress and social avoidance and fear of disclosure.

Curvilinear Relations Between Parallel Multiple Jobs and Physical Activities Functioning/Mental Health Problems: The Evidence From an Agriculture Population.

Objective: The practice of parallel multiple jobs has increasingly become a global trend. However, the effects of parallel multiple jobs on physical and mental health have not been well understood.

Method: Data come from China Health and Retirement Longitudinal Study published by CHARLS in 2015.

The airline transport regulation and development of public health crisis in megacities of China.

Background: The Civil Aviation Administration of China (CAAC) declares the airline transport regulation in January 2020 to help retard the spread of the novel coronavirus disease in China. This study is to examine the effect of airline transport regulation on confirmed cases of the novel coronavirus disease in megacities in China.

Methods: This study combines the multi-source data from the health data platform DXY, the airline data platform Airsavvi, the China Economic Internet Statistical Database and the China Railway website.