Publications by authors named "Chulalak Komoltri"
Article Synopsis
- The study explored how time in the target range for systolic blood pressure (SBP-TTr) affects clinical outcomes in patients with atrial fibrillation (AF) using data from a multicenter registry in Thailand.
- Researchers tracked blood pressure over time and found that higher SBP-TTr levels were linked to lower rates of death, major bleeding, and heart failure among AF patients.
- The findings highlight that maintaining good blood pressure control is crucial for improving the health outcomes of individuals with atrial fibrillation.
Article Synopsis
- The study focused on identifying risk factors and developing a predictive model for heart failure (HF) in Asian patients with atrial fibrillation (AF) during a 2014-2017 registry in Thailand.
- Out of 3402 patients, 218 experienced heart failure, resulting in an incidence rate of 3.03 per 100 person-years, with a follow-up period averaging around 26 months.
- A predictive model was created using clinical factors related to HF, achieving strong performance metrics, including a C-index of 0.756, indicating good predictive capability and accuracy in clinical settings.
Objective: To determine the effect of gender on clinical outcomes of Asian non-valvular atrial fibrillation patients.
Design: This is a cohort study.
Setting: 27 university and regional hospitals in Thailand.
Optimal INR level in elderly and non-elderly patients with atrial fibrillation receiving warfarin: a report from the COOL-AF nationwide registry in Thailand.
J Geriatr Cardiol
October 2020
Background: Asian population are at increased risk of bleeding during the warfarin treatment, so the recommended optimal international normalized ratio (INR) level may be lower in Asians than in Westerners. The aim of this prospective multicenter study was to determine the optimal INR level in Thai patients with non-valvular atrial fibrillation (NVAF).
Methods: Patients with NVAF who were on warfarin for stroke prevention were recruited from 27 hospitals in the nationwide COOL-AF registry in Thailand.
Effect of combined facial exercise with botulinum toxin A on health-related quality of life in Thai adults with hemifacial spasm: a randomised controlled pilot cross-over trial.
J Neurol Neurosurg Psychiatry
March 2021
We aimed to determine if low body weight (LBW) status (<50 kg) is independently associated with increased risk of ischemic stroke and bleeding in Thai patients with non-valvular atrial fibrillation (NVAF). (1) Background: It has been unclear whether LBW influence clinical outcome of patients with NVAF. (2) Methods: This prospective multicenter cohort study included patients enrolled in the COOL-AF Registry.
View Article and Find Full Text PDFIntroduction: International normalised ratio (INR) control is an important factor in patients with non-valvular atrial fibrillation (NVAF) being treated with warfarin. INR control was previously reported to be poorer among Asians compared to Westerners. We aimed to validate the SAMe-TT2R2 score for prediction of suboptimal INR control (defined as time in therapeutic range [TTR] < 65% in the Thai population) and to investigate TTR among Thai NVAF patients being treated with warfarin.
View Article and Find Full Text PDFBackground: Anticoagulation therapy is a standard treatment for stroke prevention in patients with non-valvular atrial fibrillation (NVAF) that have risk factors for stroke. However, anticoagulant increases the risk of bleeding, especially in Asians. We aimed to investigate the risk profiles and pattern of antithrombotic use in patients with NVAF in Thailand, and to study the reasons for not using warfarin in this patient population.
View Article and Find Full Text PDFObjective: To compare sensitivity, specificity, accuracy and diagnostic confidence in the differentiation between benign and metastatic bone lesions on whole body planar bone scintigraphy and Evolution SPECT/CT.
Material And Method: Eighty diagnosed or suspected cancer patients with indeterminate lesions on planar scintigraphy were recruited in the present prospective study. Additional whole body Evolution SPECT/CT was performed after whole body planar scintigraphy.
Objective: To compare the efficacy and cost-effectiveness of high and low dose regimens of I-131 treatment in patients with hyperthyroidism.
Material And Method: One hundred fifty patients with proven hyperthyroidism were randomly allocated into the high (74 patients) and low (76 patients) dose regimen of I-131 treatment. Four patients of the high dose group and one patient of the low dose group were excluded because of lost follow-up.
Objective: To determine the correlation between actual birthweight (BW) and fetal weight calculated from fractional thigh volume (ThiV).
Material And Method: The authors have conducted a prospective, cross-sectional study of normal Thai fetal thigh volume. There were 176 eligible pregnant women who met the criteria of singleton with no fetal anomaly were recruited into the present study.
Objective: To compare castor oil and sodium phosphate preparation (Swiff) in patients' satisfaction, efficacy for colon cleanness, side effects, and prices.
Material And Method: One hundred patients referred for barium enema were randomized to receive castor oil (n = 50) and sodium phosphate preparation (n = 50). They graded their satisfaction using a 5-point scale (easy, acceptable, slightly difficult, extremely difficult, and unacceptable).
Background: There are little data on the validation of 12-lead electrocardiogram (ECG) derived by the EASI lead system used for continuous monitoring in critical care settings.
Objective: The objectives of this study were to determine the accuracy of 12-lead ECG derived by the EASI lead system in the detection of ST-segment deviation and cardiac rhythm compared with the standard 12-lead ECG.
Methods: All patients admitted to the coronary care unit were studied.