Publications by authors named "Chukwuma E Odunze"
Article Synopsis
- * Caspase-11 is a specific inflammatory caspase that gets activated by bacterial LPS, leading to its aggregation and the cleavage of gasdermin D, which causes a form of cell death known as pyroptosis.
- * Research found that the activation and self-processing of Caspase-11 are essential for its assembly into speckles in macrophages in response to LPS, indicating a crucial role for its enzymatic activity in inflammasome organization.
