Microplastic dynamics and risk projections in West African coastal areas: Developing a vulnerability index, adverse ecological pathways, and mitigation framework using remote-sensed oceanographic profiles.

Microplastic pollution presents a serious risk to marine ecosystems worldwide, with West Africa being especially susceptible. This study sought to identify the key factors driving microplastic dynamics in the region. Using NASA's Giovanni system, we analyzed environmental data from 2019 to 2024.

Effects of α-olefin sulfonate (AOS) on Tubifex tubifex: toxicodynamic-toxicokinetic inferences from the general unified threshold (GUTS) model, biomarker responses and molecular docking predictions.

We investigated the potential ecological risks and harm to aquatic organisms posed by anionic surfactants such as α-olefin sulfonate (AOS), which are commonly found in industrial and consumer products, including detergents. This study assessed acute (96-h) and subchronic (14-day) responses using antioxidant activity, protein levels, and histopathological changes in Tubifex tubifex exposed to different AOS concentrations (10% of the LC, 20% of the LC, and a control). Molecular docking was used to investigate the potential interactions between the key stress biomarker enzymes (superoxide dismutase, catalase, and cytochrome c oxidase) of Tubifex tubifex.

Pathological and ultrastructural changes of Bellamya bengalensis under chronic carboxylic acid exposure at environmentally relevant levels: Inferences from general unified threshold model for survival (GUTS) predictions and hepatopancreatic integrity assessment.

This study aimed to understand the effects of freshwater acidification, driven by industrial runoff, agricultural activities, and atmospheric deposition, on the freshwater mollusk Bellamya bengalensis. By systematically investigating the impact of two common carboxylic acids, acetic acid (AA) and benzoic acid (BA), this research employed diverse toxicological, pathological, and ecological assessments. We explored survival predictions through the generic unified threshold model of survival (GUTS-SD), examined oxidative stress responses, and investigated hepatopancreatic alterations.

Predicting the dynamics of per- and polyfluoroalkyl substances in coastal regions of Africa: vulnerability index and adverse ecological pathways from remote-sensed variables.

This study aimed to predict the dynamics of per- and polyfluoroalkyl substance (PFAS) contamination and ecological vulnerability within coastal regions of Africa utilizing time-averaged remote-sensed data patterns from 2020 to 2023. The analysis identified PFAS contamination hotspots along the coast of Africa, particularly in western Africa around Nigeria and in areas spanning Equatorial Guinea and Guinea-Bissau, with risk influenced by eastward wind patterns, overland runoff, and elevated aerosol optical depth (AOD) values. Regional trends indicated that variations in solar energy absorption and surface air temperature could influence PFAS dynamics in North Africa, South Africa, East Africa, and West Africa.

Role of niche and micro-habitat preferences in per- and polyfluoroalkyl substances occurrence in the gills of tropical lake fish species.

The present study has investigated per- and poly-fluoroalkyl substances (PFAS) in the gill tissues of various fish species inhabiting different trophic levels within Eleyele Lake, a tropical freshwater lake in Nigeria. The mean concentrations of PFAS congeners were determined, and their trends and patterns were analyzed across different trophic species. The results revealed variations in congener abundance and species-specific patterns that was influenced by habitat and niche preferences.

Urbanization effects on growth and otolith asymmetry in Chrysichthys nigrodigitatus and Oreochromis niloticus within tropical coastal lagoon watersheds.

In this study, we investigated the growth dynamics and otolith shape asymmetry of two fish species, Chrysichthys nigrodigitatus (CN) and Oreochromis niloticus (ON), within urbanized watersheds of the southern lagoon system, Nigeria. Using the von Bertalanffy growth model (VBGM), in addition to sediment metal concentration indices such as the average shale content, index of geoaccumulation (Igeo), contamination factor (CF), pollution load index (PLI), and potential ecological risk (PER) index, contamination levels were classified, and ecological risks were assessed. Notably, a lower growth potential (t0) was observed in CN at Ikorodu than at Epe, with similar trends for ON in the Epe during the dry season.

Gonad pathology, sex hormone modulation and vitellogenin expression in from Lagos and Epe lagoons within the southern-lagoon system, Nigeria.

Estrogenic chemicals in aquatic environments impact fish reproductive health, with vitellogenin protein levels serving as a crucial biomarker for xenoestrogen exposure. Limited knowledge exists on estrogenic effects in tropical environments, prompting an investigation into the influence of environmental estrogens on in Lagos and Epe lagoons. A total of 195 fish samples underwent analysis for vitellogenin protein, sex hormones (testosterone and 17 β-estradiol), and gonad pathology in effluent-receiving areas of the specified lagoons.

Occurrence, bioaccumulation and trophic dynamics of per- and polyfluoroalkyl substances in two tropical freshwater lakes.

We have investigated the occurrence, distribution, and biomagnification of per- and polyfluoroalkyl substances (PFAS) in two tropical lakes (Asejire and Eleyele) of Southwestern Nigeria, with contrasting urban intensities. Over an 8-month period, we sampled sediment and fish species (Clarias gariepinus: CIG; Oreochromis niloticus: ON; Coptodon guineensis: CG; Sarotherodon melanotheron: SM) across trophic levels, and analyzed various PFAS congeners, in addition to a select group of toxicological responses. While herbivores (SM) and benthic omnivores (CIG) at Asejire exhibited elevated levels of PFBS and PFOS, the pelagic omnivores (ON) showed a dominance of PFOS, PFDA, PFHxDA and EtFOSE in the muscle.

Fluorene-induced stress in the benthic oligochaete Tubifex tubifex: A multi-biomarker assessment of toxicological pathways and mechanisms under acute and subchronic exposures.

This study examined the multifaceted impacts of fluorene exposure on Tubifex tubifex, encompassing acute (survival analysis and behavioral responses) and subchronic exposure regimens (antioxidant enzyme response and histopathology), molecular docking studies, and generalized read-across analysis. Survival analysis revealed concentration-dependent increases in toxicity over varying time intervals, with LC50 values decreasing from 30.072 mg/L at 24 h to 12.

Habitat sensitivity in the West African coastal area: inferences and implications for regional adaptations to climate change and ocean acidification.

This study focuses on assessing coastal vulnerability and habitat sensitivity along the West African coast by delineating hotspots based on surface temperature, pH, chlorophyll-a, particulate organic carbon, and carbonate concentrations between 2018 and 2023 depending on data availability. Initial exploration of these variables revealed two distinct focal points i.e.

Redox-active metals and oxidative stress-mediated myopathies in Callinectes amnicola, blue crab populations from impacted sites of the Lagos Lagoon: inferences for adverse ecological outcomes.

While oxidative stress pathways are associated with a wide variety of tissue pathologies, its applications for evaluating and discerning ecological risks are limited. This study seeks to associate trends of lipid peroxidation and oxidative stress to risks of muscle pathologies in blue crabs inhabiting regions of the Lagos Lagoon. Crab samples (n = 520) were selected from pollution-impacted sites of the lagoon at Iddo, Ajah, Okobaba, Makoko, and the mid-lagoon area (control site).

Triazophos-induced Respiratory and Behavioral Effects and Development of Adverse Outcome Pathway (AOP) for short-term Exposed Freshwater Snail, Bellamya Bengalensis.

The physiological effects of triazophos were examined using respiratory and behavioral endpoints in Bellamya bengalensis under a 96-hour acute exposure regime. Physiological manifestation of respiratory stress was measured using the rate of oxygen consumption while behavioral toxicity was measured using crawling reflexes, touch response, and mucus production. The threshold effect values for LOEC (Lowest Observed Effect Concentration), NOEC (No Observed Effect Concentration), and MATC (Maximum Acceptable Toxicant Concentration) at 96 h were 0.

Trend relationship between mountain normalized difference vegetation index (NDVI) and aerosol optical depth (AOD) across two decades: implication for water quality within the Lesotho Highlands, Drakensberg, South Africa.

There are growing concerns on contribution of vegetation dynamics to atmospheric turbidity and quality of regional water towers. The study sought to determine the trends in the MODIS/TERRA-derived normalized difference vegetation index (NDVI) and aerosol optical depth (AOD) for Lesotho Highland over 2000-2020. The predictive relationship between the two variables was also examined using regression analysis.

Behavioral toxicity, histopathological alterations and oxidative stress in Tubifex tubifex exposed to aromatic carboxylic acids- acetic acid and benzoic acid: A comparative time-dependent toxicity assessment.

This study evaluated Acetic acid (AA) and Benzoic acid's (BA) acute and sublethal toxicity by observing mortality, behavioral responses, and changes in the levels of oxidative stress enzymes in Tubifex tubifex. Exposure-induced changes in antioxidant activity (Catalase, Superoxide dismutase), oxidative stress (Malondialdehyde concentrations), and histopathological alterations in the tubificid worms were also noted across exposure intervals. The 96 h LC values of AA and BA to T.

Deltamethrin-Induced Respiratory and Behavioral Effects and Adverse Outcome Pathways (AOP) in Short-Term Exposed Mozambique Tilapia, .

Disrupted behavior and respiratory distress effects of 96-h acute deltamethrin exposures in adult Mozambique tilapia, , were investigated using behavioral indices and opercular movement, respectively. Deltamethrin concentrations were found to be associated with toxicological (lethal and sublethal) responses. At 24, 48, 72, and 96 h, the LC50 values and 95% confidence limits were 12.

Sub-lethal acute effects of environmental concentrations of inorganic mercury on hematological and biochemical parameters in walking catfish, Clarias batrachus.

The acute toxicity of mercury to the air-breathing fish Clarias batrachus (Linn.) was determined in this study using hematological (including hemoglobin, hematocrit, total erythrocyte count, total leukocyte count, and mean corpuscular hemoglobin concentration) and biochemical (including total serum protein, serum glucose, triglyceride, cholesterol, albumin) biomarkers at predetermined exposure concentrations (0.069 and 0.

Public health implications of endocrine disrupting chemicals in drinking water and aquatic food resources in Nigeria: A state-of-the-science review.

This state-of-the-science review is aimed at identifying the sources, occurrence, and concentrations of EDCs, including potential public health risks associated with drinking water and aquatic food resources from Nigerian inland waters. A total of 6024 articles from scientific databases (PubMed, Scopus, Web of science, ScienceDirect, Google Scholar, and African Journals Online) were identified, out of which, 103 eligible articles were selected for this study. Eleven (11) classes of EDCs (OCPs, PCBs, PBDEs, PAHs, BPA, OTs, PEs, PCs, PPCPs, sterols and n-alkanes) were identified from drinking waters, river sediments and aquatic food species from Nigerian rivers, showing that OCPs were the most studied and reported EDCs.

Longer-Term Adverse Effects of Selenate Exposures on Hematological and Serum Biochemical Variables in Air-Breathing Fish Channa punctata (Bloch, 1973) and Non-air Breathing Fish Ctenopharyngodon Idella (Cuvier, 1844): an Integrated Biomarker Response Approach.

To examine the spectrum of selenium toxicity between hardy and less hardy species of the same life stages, short-term and longer-term exposures in juvenile air-breathing fish Channa punctata (Bloch, 1973) and non-air-breathing fish Ctenopharyngodon idella (Cuvier, 1844) were assessed. Acute exposures revealed a greater 96-h median lethal concentration (LC) for C. punctata (14.

Behavioral and physiological toxicity thresholds of a freshwater vertebrate (Heteropneustes fossilis) and invertebrate (Branchiura sowerbyi), exposed to zinc oxide nanoparticles (nZnO): A General Unified Threshold model of Survival (GUTS).

The toxic effects of Zinc oxide nanoparticles (nZnO) on Branchiura sowerbyi and Heteropneustes fossilis, was assessed in a 96-hour acute exposure regime using behavioral (including loss-of balance and clumping tendencies) and physiological (mucus secretion and oxygen consumption) endpoints. While the relationship between behavioral, physiological biomarkers, and exposure concentrations was assessed using correlation analysis, nZnO toxicity was further predicted using the General Unified Threshold model for Survival (GUTS). The time-dependent lethal limits for acute nZnO toxicity (LC) on B.

Antioxidant enzyme activity and pathophysiological responses in the freshwater walking catfish, Clarias batrachus Linn under sub-chronic and chronic exposures to the neonicotinoid, Thiamethoxam®.

The hydrophilic nature and resultant persistence of neonicotinoids in aquatic systems increase the exposure duration for non-target organisms. The sublethal toxicity of the neonicotinoid Thiamethoxam® spanning sub-chronic and chronic durations was investigated in Clarias batrachus, a non-target freshwater fish species. 96 h LC value of Thiamethoxam® on Clarias batrachus was 138.

Physiological (haematological, growth and endocrine) and biochemical biomarker responses in air-breathing catfish, Clarias batrachus under long-term Captan® pesticide exposures.

The sub-lethal toxicity of Captan® on selected haematological (Hemoglobin, Haematocrit, Mean Corpuscular Hemoglobin) growth (Condition factor, Hepatosomatic Index, Specific Growth Rate), biochemical (serum glucose, protein), and endocrine parameters (growth hormone, T and T) in Clarias batrachus was examined under chronic exposures. Captan® was administered at predetermined exposure concentrations (0.53 and 1.

Effects of short-term selenium exposure on respiratory activity and proximate body composition of early-life stages of Catla catla, Labeo rohita and Cirrhinus mrigala.

Metal exposure impairs respiration, increases metabolic demand, and reduces energy storage/fitness in aquatic species. Respiratory impairment and energy storage was examined in acute selenium-exposed Indian major carps, Catla catla, Labeo rohita and Cirrhinus mrigala fry and were correlated with exposure concentrations. Toxicity effects were determined in a renewal bioassay using 96 h lethal selenium concentrations.

Fluoride sensitivity in freshwater snail, Bellamya bengalensis (Lamarck, 1882): An integrative biomarker response assessment of behavioral indices, oxygen consumption, haemocyte and tissue protein levels under environmentally relevant exposure concentrations.

There is limited information on fluoride toxicity and risk overview on ecotoxicological risks to aquatic invertebrate populations particularly molluscan taxa. This necessitated the assessment of toxicity responses in the freshwater snail, Bellamya bengalensis exposed to environmentally relevant concentrations of sodium fluoride. Under lethal exposures (150, 200, 250, 300, 400 and 450 mg/l), the median lethal concentrations (LC) were determined to be 422.

Biochemical, physiological (haematological, oxygen-consumption rate) and behavioural effects of mercury exposures on the freshwater snail, Bellamya bengalensis.

The widespread occurrence of Mercury (Hg) and its derivatives in the aquatic environment and risks to the health of local populations has necessitated investigations into its toxic effects on sessile species. The toxicity of Mercury was observed sequentially from 96 h acute exposure regime (behavioural endpoints) to chronic durations (haematological and biochemical toxicity endpoints) in Bellamya bengalensis. Time-dependent lethal endpoints for acute toxicity (LC50) of mercury i.