Publications by authors named "Chugh A"

Background: The infrazygomatic miniscrew implants (IZC-MSI) serve as innovative temporary anchorage devices placed parallel to the roots of molars in the infrazygomatic crest region, leveraging their extra-radicular location to support the en masse distalization and intrusion of the maxillary dentition. The efficacy and stability of these screws are crucial for their application in contemporary orthodontic practices.

Objectives: This systematic review aimed to estimate the success rate and factors affecting the stability of IZC-MSI.

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Regular exercise leads to various adaptations and many pathophysiological changes that significantly benefit exercise stamina and overall health, both in the general population and in patients with chronic cardiovascular diseases. High-intensity interval training (HIIT) is a form of exercise training that consists of short repetitive bursts of intense workouts that push the body to more than 90 percent of its maximal oxygen consumption (VO2 max) and more than 75 percent of maximal power, with in between periods of low-intensity exercise for recovery, followed by a cool-down period. HIIT has unquestionably emerged as a powerful and effective intervention in rehabilitating patients, particularly those recovering from heart attacks and strokes.

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Orbital defects can result from a myriad of underlying diseases and injuries. Treatment of malignant neoplasms and maxillofacial trauma are common reasons for orbital exenteration. Recently, a growing number of cases of orbital defects have been reported due to mucormycosis in patients with COVID-19.

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To evaluate the quality of life in the post maxillectomy patients due to Coronavirus disease 2019 (COVID-19) associated Mucormycosis (CAM) following rehabilitation with obturators. The study also described the management and treatment outcomes of CAM patients. The study included 80 confirmed patients of CAM.

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Article Synopsis
  • The study was a prospective pre-post design aimed at improving the quality of documentation for maxillofacial trauma in the emergency department using a structured template.
  • By evaluating 220 patients, it found an 18.95% improvement in record completeness when using the template, particularly in key areas like time of evaluation and ophthalmic assessments.
  • The findings suggest that the structured template enhances thoroughness and accuracy in documenting injuries, leading to better clinical care and reduced risk of medical negligence.
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Giant cell tumors (GCTs) of bone are classified as intermediate malignant tumors with a significant potential for local infiltration. Despite their benign histopathological appearance, these tumors exhibit extreme local aggression. The sacrum is the most commonly affected spinal region, followed by the lumbar, cervical, and thoracic regions.

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We study the dependence of alignment and confinement on the aggregate morphology of self-aligning soft disks(particles) in a planer box (two dimensional) geometry confined along y direction using Langevin dynamics simulations. We show that when the box width decreases, the aggregate wall accumulation becomes non-uniform and displays non-monotonic behaviour in terms of phase behavior and height of these aggregates with an increase in alignment strength. Additionally, we identify two distinct categories of wall aggregates: layered and non-layered structures each exhibiting distinct local structural properties.

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Introduction: Cancer is one of the major public health concerns leading to high trends of mortality and morbidity in India. Health-related quality of life (HRQoL) is an indicator of the sense of well-being applicable, which includes all the domains of physical, social, emotional, and functional well-being. The inferences can strengthen the palliative care needs of patients.

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  • Cholesterol Granuloma is a rare tissue lesion found in areas like the ear, lungs, and breast, resulting from cholesterol interacting with living tissue.
  • The occurrence of Cholesterol Granuloma in the orbit (the eye socket) is extremely rare.
  • The authors share a specific case of Cholesterol Granuloma that developed in the orbit to highlight its uniqueness.
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  • - Dofetilide, a class III antiarrhythmic, is used to treat atrial fibrillation and flutter, and has been applied off-label for ventricular arrhythmias like PVCs and VTs.
  • - In a study involving 81 patients, dofetilide initiation showed a significant decrease in PVC burden, but was discontinued in some cases due to QT prolongation and lack of efficacy.
  • - Overall, 72% of patients had to stop dofetilide due to inefficacy or intolerance, and there was no significant difference in event-free survival between those treated with dofetilide and those who weren't.
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Pilomyxoid astrocytoma (PMA) is a subtype of pilocytic astrocytoma (PA). PMA tends to exhibit a more aggressive course compared to PA. We present a case of a two-year-old male with a PMA in the suprasellar region who presented with developmental regression, loss of previously attained milestones such as the ability to hold his neck, walk, and talk, along with hypotonia in all four limbs.

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  • The tobacco industry is actively working to influence tobacco control policies in India, prompting an assessment of the trends in tobacco industry interference (TII) and government responses to protect tobacco control efforts as outlined in Article 5.3 guidelines.
  • A detailed analysis covering the years 2018 to 2021 revealed a decline in India's TII score from 72 to 57, indicating some improvements in limiting interactions with the industry and avoiding conflicts, but persistent issues in regulating industry participation and transparency remain.
  • The study highlights the need for a comprehensive implementation of Article 5.3 across India, emphasizing the importance of establishing a monitoring system to continuously assess and respond to tobacco industry activities.
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Objective: To determine if mild-moderate hypertriglyceridemia (HTG) is associated with increased development of chronic pancreatitis (CP) or pancreatitis-associated complications in children with acute recurrent or CP.

Study Design: Longitudinal data from the INternational Study group of Pediatric Pancreatitis: In search for a cuRE-2 (INSPPIRE-2) cohort of children with acute recurrent or CP (n = 559) were analyzed. Subjects were divided into normal triglycerides (<150 mg/dL; 1.

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  • DADA2 is a genetic disorder similar to polyarteritis nodosa that affects children, and this study focuses on describing its clinical presentation and outcomes among Indian patients.* -
  • A total of 16 children with DADA2 were studied, showing common symptoms like fever and rash, with over half experiencing CNS strokes; they were treated with immunomodulators like steroids and anti-TNF agents.* -
  • Most children responded positively to treatment, achieving remission, and the study highlights key differences between DADA2 and classic polyarteritis nodosa, especially in terms of age of onset and CNS involvement.*
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Introduction Central nervous system (CNS) tumors pose significant diagnostic challenges due to their varied morphological and differentiating characteristics. Modern advancements in immunohistochemistry (IHC) and molecular pathology have greatly enhanced prognostication, screening, and therapeutic management. Gliomas, a type of tumor originating from glial cells in the CNS, can develop from astrocytes, oligodendrocytes, or ependymal cells.

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Background: The purpose of the study was to compare the efficacy of the use of 0.2% chlorhexidine irrigation and the oral antibiotics for the prevention of postoperative complication like pain, trismus, swelling and infection after the surgical extraction of IMTM.

Material And Methods: A randomised, double blinded clinical trial was planned with two equal groups.

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Objectives: While guidelines exist for the diagnosis and management of pediatric celiac disease (CeD), current practices in North America are not well-described. This study aimed to explore current practice patterns to identify gaps and direct future clinical, training and research initiatives.

Methods: A 23-item survey designed by the Celiac Disease Special Interest Group was distributed electronically to its members.

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Coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM) has emerged as a formidable infection in patients with COVID-19, this study was designed to assess the QOL in patients with and its predictability for survival in CAM victims. This long term prospective observational study of 290 patients with CAM was conducted over 2 years using a standard questionnaire (the abbreviated World Health Organization Quality of Life questionnaire [WHO-BREF]), Karnofsky performance scale (KPS), palliative performance scale (PPS) and patient rated improvement (PRI) ranging from 0 to 9. Cut-off values of ≤ median score was considered to indicate poor QOL or poor improvement.

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Purpose: The successful osseointegration around immediate implants requires high quality and quantity of osteogenesis around them. The role of magnesium as a boneenhancing mineral, and as an adjunctive analgesic has been well documented in orthopedic literature. However, there is a paucity of literature in its role in successful osseointegration around immediate implants.

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Article Synopsis
  • Chiari malformation (CM) is a neurological condition often treated with foramen magnum decompression (FMD), which may not always be effective.
  • In a specific case of CM-1, the patient showed initial improvement after FMD but later worsened, leading to the decision for an additional procedure called atlantoaxial fixation.
  • The outcome highlights the need to focus on treating the underlying causes of CM rather than just relieving pressure on the tonsils.
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The longevity of an extraoral prosthesis depends on its physical and mechanical properties and user maintenance. Faced with multiple outcome measures, researchers find it difficult to determine the most appropriate extraoral prosthetic material. This comprehensive review evaluates the most used extraoral prosthesis materials and qualitatively assesses their longevity and function.

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We evaluated patients aged 12-20 on dupilumab 300 mg weekly for treatment of eosinophilic esophagitis (EoE) who had ≥1 follow-up endoscopy at a tertiary care pediatric hospital (n = 18). Fifty percent had inflammatory EoE (n = 9), 22% had fibrostenotic EoE (n = 4), and 28% had non-EoE eosinophilic gastrointestinal disease (EGID) with esophageal involvement (n = 5). Ninety-four percent discontinued topical corticosteroids (TCS) 2-4 weeks after starting dupilumab.

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