Bridged emulsion gels from polymer-nanoparticle enabling large-amount biomedical encapsulation and functionalization.

Large-amount encapsulation and subsequent expressing are common characteristics for many biomedical applications, such as cosmetic creams and medical ointments. Emulsion gels can accomplish that, but often undergo exclusive, complex, multiple synthesis steps, showing extremely laborious and non-universal. The method here is simple via precisely interfacial engineering in homogenizing a nanoparticle aqueous dispersion and a polymer oil solution, gaining interfacial 45° three-phase-contact-angle for the nanoparticle that can bridge across oil emulsions' interfaces and ultimately form interconnected macroscopic networks.

Magnetic Janus Particles: Synthesis and Multifunctional Applications.

Magnetic Janus particles (MJPs) with compositional compartmentalization and strong magnetic responsiveness play a pivotal role in various application fields, such as biotechnology, medicine, and materials science. However, comprehensive reviews of the field of MJPs remain limited. Here, this article attempts to fill the gap by reviewing the current common synthetic strategies for MJPs, including masking, microfluidics, self-assembly, phase separation, and seeded emulsion polymerization, among others.

Dynamic Electrostatic Interfacial Engineering for Block Copolymer Microparticles with Reversible Structures.

Responsive nanoparticle surfactants (NPSs) can dynamically and reversibly modulate the interfacial interactions between incompatible components, which are essential in the interfacial catalysis, corrosion, and self-assembly of block copolymers (BCPs). However, NPSs with stimuli-responsive behavior often involve tedious chemical synthesis and surface modifications. Herein, we propose a strategy to in situ construct a kind of dynamic and reversible NPSs by the interfacial electrostatic interaction between the negatively charged nanoparticles (NPs) and the positively charged homopolymers.

Serum metabolomic analysis in patients with Hashimoto's thyroiditis.

Background: Hashimoto's thyroiditis, an autoimmune thyroid disease, shows high morbidity worldwide, particularly in female. Patients with Hashimoto's thyroiditis have an increasing risk of hypothyroidism during the occurrence and progression of Hashimoto's thyroiditis. In recent years, metabolomics has been widely applied in autoimmune diseases, especially thyroid disorders.

'And I thought having a cancer diagnosis was hard': A descriptive phenomenological study of family caregiver experiences navigating the pre-hospital system during COVID-19.

Purpose: Cancer patients usually need frequent hospitalization for diagnosis and treatment. However, the unprecedented outbreak of the Omicron wave in Shanghai pressured local communities and hospitals to enforce strict control measures. This qualitative study aimed to investigate cancer family caregivers' experiences of navigating the pre-hospital system during the lockdown in Shanghai.

Preparation of Janus Droplets and Hydrogels with Controllable Morphologies by an Aqueous Two-Phase System on the Superamphiphobic Surface.

Janus particles, having the property integration of each component, have attracted increasing attention due to their considerable potential in the field of material engineering applications. However, organic solvents or sophisticated equipment during the fabrication processes is generally inevitable. Here, we report a facile route to prepare Janus droplets and hydrogels via aqueous two-phase systems (ATPS).