Sevoflurane Inhibits Metastasis in Hepatocellular Carcinoma by Inhibiting MiR-665-Induced Activation of the ERK/MMP Pathway.

Recent evidence has indicated that inhalational anesthetics may affect the growth and malignant potential of tumor cells and ultimately influence tumor recurrence after surgery. Sevoflurane, a volatile anesthetic, is used extensively in hepatectomy. However, the effect of sevoflurane on the growth of hepatocellular carcinoma (HCC) cells remains unknown.

[Wnt3a signaling pathway plays a role in neuropathic pain through epigenetic modification of JMJD6].

To explore whether Wnt3a exerts a role in neuropathic pain through Jumonji C domain 6 (JMJD6)-associated epigenetic modification. 
 Methods: SD rats were divided into 4 groups: A sham group, a chronic constriction injury (CCI) group, a CCI+negative lentiviral expression vector (LV-NC) group and a CCI+lentiviral overexpression vector (LV-JMJD6) group. The sciatic nerve CCI model of SD rat and JMJD6 lentiviral expression vector were constructed.

The prognostic significance of preoperative neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma receiving hepatectomy: A systematic review and meta-analysis.

Background And Aims: Numerous reports have indicated that preoperative Neutrophil-Lymphocyte ratio (NLR) was correlated with the prognosis of hepatocellular carcinoma who underwent hepatectomy. However, the results still remained controversial. Therefore, the present meta-analysis of 17 studies was performed to evaluate the prognostic value of preoperative NLR in HCC patients.

Sensitive surface-enhanced Raman scattering of TiO/Ag nanowires induced by photogenerated charge transfer.

In this work, the semiconductor TiO nanowires were successfully coupled with plasmonic metal Ag nanoparticles to fabricate hybrid nanostructures with enhanced sensitive Raman substrate. The SERS activities of fabricated hybrid nanostructures were evaluated by detecting the Raman signals of R6G molecules. The fabricated TiO/Ag nanowire/nanoparticle hybrid nanostructures show sensitive detection ability for R6G molecules.