Publications by authors named "Chubo Yang"
Article Synopsis
- Behcet's syndrome causes oral ulcers and involves complex inflammatory processes; this study investigates the relationship between inflammatory cytokines, metabolites, and the disease's development using Mendelian randomization.
- The research analyzed associations between 91 cytokines and 553 metabolites through genetic variants (SNPs) and employed various statistical tests to ensure reliability.
- Five substances, including specific interleukins and a metabolite, were found to be causally related to the syndrome, providing potential markers for diagnosis and treatment, but more research is needed to confirm their efficacy as targets for therapy.
Objective: Histone-deacetylases (HDACs) are epigenetic modulators involved in the control of gene expression. No data are available on the expression or subcellular localization of HDACs in salivary glands. The present study aims to examine the subcellular distribution of HDACs in salivary glands during postnatal development.
View Article and Find Full Text PDFHydrogels are widely used as wound dressings for wound healing, but when hydrogels absorb wound exudate, swelling occurs and compresses the surrounding tissue, affecting healing. A chitosan injectable (CS/4-PA/CAT) hydrogel based on catechol and 4-glutenoic acid was prepared to avoid swelling and promote wound healing. After cross-linking by UV light, pentenyl groups formed hydrophobic alkyl chains which give the hydrogel a hydrophobic network and thus control its swelling.
View Article and Find Full Text PDF