Effects of HIV infection on metastatic cervical cancer and age at diagnosis among patients in Lusaka, Zambia.

Objective: To examine the association between the duration of HIV infection and the stage of cervical cancer in Lusaka, Zambia.

Methods: This retrospective case-case study included 1583 cervical cancer patients from the Cancer Diseases Hospital in Lusaka, Zambia. A sub-population of HIV-positive patients with additional clinical HIV information was identified following linkage of cancer and HIV databases.

Effects of HIV status on non-metastatic cervical cancer progression among patients in Lusaka, Zambia.

Introduction: Sub-Saharan Africa has the highest global incidence of cervical cancer. Cervical cancer is the most common cause of cancer morbidity and mortality among women in Zambia. HIV increases the risk for cervical cancer and with a national Zambian adult HIV prevalence of 16%, it is important to investigate the impact of HIV on the progression of cervical cancer.

[Mutation processes in the natural populations of Drosophila and Hirundo rustica from Ukrainian radiation contaminated territories].

Natural populations of Drosophila melanogaster and Hirundo rustica that reside at the territories with different levels of radioactive pollution were investigated. The levels of visible mutations, sex-linked mutations and gonad reduction of Drosophila and the rate of interphase markers of chromosomal instability in erythrocytes of birds were selected as parameters for population monitoring. The results point out to possible reverse dependence among the level of chromosomal instability of birds, the rate of lethal mutations in sex chromosome of Drosophila and the density of radioactive pollution.