Publications by authors named "Chuanzhu Lyu"
Article Synopsis
- In 2009, the World Health Organization recognized snakebite as a neglected tropical disease, particularly affecting farmers and plantation workers, leading to significant mortality and long-term disabilities.
- The guideline offers practical information for healthcare professionals to assess and manage snakebite cases, drawing from both clinical experience and research evidence.
- Key areas covered include understanding snake venom, recognizing symptoms, conducting examinations, diagnosing snakebites, and prevention strategies.
Background: Several observational studies have shown an association between homocysteine (Hcy) levels and chronic obstructive pulmonary disease (COPD), but causal relationships are not clear. Our study aimed to explore the causal relationship between plasma Hcy and COPD by two-sample Mendelian randomization (MR).
Methods: A two-sample MR study was performed to infer the causal link.
Background: We aimed to examine prospective associations between different intensities and different types of physical activity (PA) in early pregnancy and hypertensive disorders of pregnancy (HDP) among Chinese women.
Methods: A total of 6,820 pregnant women from the Tongji-Shuangliu Birth Cohort were included in this study. The pregnancy physical activity questionnaire (PPAQ) was used to assess PA, including household/caregiving, occupational, sports/exercise, and transportation activities in the first trimester of pregnancy.
Background: The high morbidity, high mortality and low survival rate of cardiac arrest (CA) cause a heavy global burden. We aimed to analyze the changes in scientific output related to CA over the past two decades.
Methods: We analyzed the scientific output related to CA from 2000 to 2020 via the Web of Science.
Findings of epidemiological studies regarding the association between carrot consumption and lung cancer risk remain inconsistent. The present study aimed to summarise the current epidemiological evidence concerning carrot intake and lung cancer risk with a meta-analysis. We conducted a meta-analysis of case-control and prospective cohort studies, and searched PubMed and Embase databases from their inception to April 2018 without restriction by language.
View Article and Find Full Text PDF[Expert consensus on the construction of emergency department in Chinese county hospitals].
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
May 2019
County-level hospitals, as medical and health centers in the counties, are mainly responsible for providing medical care for common and frequently-occurring diseases as well as rescuing acute critical patients. In 2018, editors of the Chinese Journal of Emergency Medicine evaluated the current situation of the emergency departments of county-level hospitals and found an unbalanced, inadequate, irregular, and unstable status existed among them. In order to provide developmental principles and constructional goals for the emergency departments of county-level hospitals, which located in different regions and with uneven foundations, Emergency Medical Branch of Chinese Medical Association particularly formulated this expert consensus.
View Article and Find Full Text PDFObjective: To study the effect of emodin on protein and gene expressions of the massagers in mobility signal transduction system of cholecyst smooth muscle cells in guinea pig with cholesterol calculus.
Methods: The guinea pigs were randomly divided into 4 groups, such as control group, gall-stone (GS) group, emodin group and ursodeoxycholic acid (UA) group. Cholesterol calculus models were induced in guinea pigs of GS, emodin and UA groups by lithogenic diet, while emodin or UA were given to the corresponding group for 7 weeks.
Article Synopsis
- The study aims to explore how insulin resistance contributes to cholesterol gallstone formation and examine the effects of Albiflorin Granule in preventing this process.
- Researchers measured serum levels of triglycerides, free fatty acids, and cholesterol, and analyzed protein expressions related to insulin signaling in guinea pig liver cells.
- Findings show that Albiflorin reduced gallstone formation, improved insulin sensitivity, and modulated key proteins in the insulin signaling pathway, indicating its potential in preventing cholesterol gallstones.
Objective: To investigate the distribution of pathogens and drug resistance in bile and the association between the pregnane X receptor (PXR) gene polymorphisms, traditional Chinese medicine (TCM) syndromes and the risk of cholesterol gallstone disease (CGD).
Methods: A total of 392 samples were enrolled in this study from January 2014 to February 2015, among which 192 patients were with CGD, and 200 samples were healthy. Strains were isolated and susceptibility testing was the disk diffusion method susceptibility testing.