Establishment of quantitative evaluation system for cochlear implant effectiveness for hearing-impaired children.

Introduction: Cochlear implant is currently the most widely proven interventions for auditory rehabilitation for children with severe sensorineural hearing impairment. However, there are obvious limitations in these current evaluation methods. This study aims to develop an evaluation system for quantitatively evaluating the effectiveness of cochlear implants for hearing-impaired children.

Exosomal circMACF1 drives PI3K/AKT/mTOR-mediated autophagy suppression in laryngeal squamous cell carcinoma.

Laryngeal squamous cell carcinoma (LSCC) is a common malignant tumor. The regulatory functions of circular RNAs (circRNAs) in cancers have been broadly reported. The hsa_circ_0011773 (circMACF1) is reported to be overexpressed in LSCC tissues, while its biological function in LSCC remains unclear.

Effects of COVID-19 infection in patients with autoimmune pulmonary alveolar proteinosis: a single-center study.

Background: Autoimmune pulmonary alveolar proteinosis (aPAP) is a rare interstitial lung disease. COVID-19 is associated with worse prognosis in previous lung diseases patients. But the prognosis of aPAP patients after infection with COVID-19 is unclear.

Cell division cycle 42 positively correlates with T helper 2 cytokine, effusion viscosity, and hearing loss degree in otitis media with effusion patients.

Objective: Cell division cycle 42 (CDC42) participates in the pathogenesis of some T-cell-mediated inflammatory diseases via regulating CD4 T-cell differentiation and inflammation response. This study aimed to evaluate the correlation of CDC42 and T helper (Th)1/Th2 cytokines with disease risk, effusion viscosity, and hearing loss degree of otitis media with effusion (OME).

Methods: CDC42, interleukin (IL)-4, and interferon-gamma (IFN-γ) in effusion and serum of 78 OME patients were determined by enzyme-linked immunosorbent assay.

MicroRNA-379-5p/YBX1 Axis Regulates Cellular EMT to Suppress Migration and Invasion of Nasopharyngeal Carcinoma Cells.

Background: Epithelial-mesenchymal transition (EMT) is a major actor modulating the metastasis of nasopharyngeal carcinoma (NPC). Increasing evidence indicates that microRNAs (miRs) are the important regulators of EMT program. However, the potential roles and underlying mechanisms of miR‑379-5p in regulating EMT of NPC cells remain unclear.

[Computer-assisted anatomical evaluation of the nasal sinuses in 1-2 years old children].

Objective: To analyze the anatomical and developmental characteristics of nasal sinuses in 1-2 years old children; and provide potential evidence for the diagnosis and treatment of sinusitis in 1-2 years old children.

Method: Coronal CT scans of 60 cases (1-2 years old children) were studied with the imaging station. Reference datas were identified on these images using imaging station.

[Bronchial foreign body of a 8-month infant: a case report].

A foreign body was found in left bronchi of a 8-month infant. A fish bone of 26 mm long was pulled out with bronchoscopy under general anesthesia. This kind of surgery done in infant is more challenging than that done in child.

[Computer-assisted anatomical evaluation of the nasal sinuses in infants].

Objective: To analyze the anatomical and developmental characteristics of nasal sinuses in infants; and provide potential evidence for the diagnosis and treatment of sinusitis in infants.

Method: Coronal CT scans for 36 infants (72 sides) were studied with the imaging station. Reference data were identified on these images using imaging station.

[Low-frequency tympanometry in normal neonates].

Objective: To find the characteristic of tympanogram results obtained from normative neonates 2 - 7 days about low frequency (226 Hz) probe tone, and to determine the normative values for tympanometric variables.

Method: Transient evoked otoacoustic emission (TEOAE) screening were performed by using AccuScreen Pro instrument for 135 neonates. Among them, 105 neonates passed the TEOAE screening in both ears.

[The character of pediatric chronic sinusitis with chronic cough].

Objective: To evaluate clinical and imaging character of chronic rhinosinusitis in the children with chronic cough and to discuss the treatment of them.

Method: Fifty-three children with chronic cough were examined by otolaryngologists and evaluated by computed tomography (CT) scan. Some of them were also evaluated by nasal endoscope.