Comput Intell Neurosci
October 2022
In order to process the blurred image, this study proposes to combine the blurred point functions in the invariant space into multiple blurred images and then restore them through the deconvolution operation. The PSF functions of the fuzzy invariant space are combined to obtain the fuzzy invariant space. Finally, a gradual restoration method is used to perform many blurred image processing steps.
View Article and Find Full Text PDFThe aim of this current study was to investigate the expression of the tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) and its receptor fibroblast growth factor-inducible 14 (Fn14) in human malignant ovarian tumors, and test TWEAK's potential role on tumor progression in cell models in-vitro. Using immunohistochemistry (IHC), we found that TWEAK and its receptor Fn14 were expressed in human malignant ovarian tumors, but not in normal ovarian tissues or in borderline/benign epithelial ovarian tumors. High levels of TWEAK expression was detected in the majority of malignant tumors (36 out of 41, 87.
View Article and Find Full Text PDFObjective: To investigate the mechanism underlying the hypercoagulable state in severe pre-eclampsia.
Methods: Plasma tissue factor (TF) and tissue factor pathway inhibitor (TFPI) expression from pre-eclampsia patients and healthy pregnant controls were determined by ELISA. Placental TF and TFPI gene and protein expression were detected by quantitative RT-PCR, immunohistochemistry, and Western analysis.
Drug resistance is a major concern in the successful treatment of ovarian cancer. In the present study we report a combinational drug regime using arsenic trioxide (ATO) and cisplatin (CDDP) to increase therapeutic potentiality in ovarian cancer cells. ATO-mediated growth inhibition and apoptosis in human suspension ovarian cancer COC1 cells were evaluated by MTT assay and annexin V assay using flow cytometry, respectively.
View Article and Find Full Text PDFThe poor prognosis of human ovarian cancer is partly due to its metastasis and recurrence. It has been demonstrated that tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor inducible-14 (Fn14) signaling system may be a potential regulator of human tumorigenesis. The objective of this study was to understand the effect of TWEAK on ovarian cancer metastasis.
View Article and Find Full Text PDFObjective: Cytokine imbalance might have a pivotal role in hypercoagulability seen in preeclampsia. Our objective was to determine the relationship of blood coagulation related factors in placental tissue and peripheral blood in preeclamptic and normal pregnancies.
Methods: We compared mRNA and protein levels of tissue-type plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1), and tissue factor (TF) in the placenta of normal and preeclamptic pregnancies.
Problem: To investigate the role of TSP-1 on decidual macrophages (DMPhi) in unexplained recurrent spontaneous abortion (RSA).
Method Of Study: A total of 20 women undergoing artificial abortion in the first trimester and 10 patients with RSA were selected. (i) The expression of TSP-1 mRNA in deciduas was detected by real-time polymerase chain reaction; (ii) Flow cytometry was used to detect the percentage of positive TSP-1, CD36, CD47 markers on macrophages.
Zhonghua Fu Chan Ke Za Zhi
September 2002
Objective: To study the role of lethal gene: including retinoic X receptor (RXR)alpha, N-myc and transcript enhancer factor (TEF)-1 in human spontaneous abortion.
Methods: The levels of RXRalpha, N-myc and TEF-1 mRNA expression on placenta villi from 38 spontaneous abortion women and 33 normal early pregnant women were examined by reverse transcription, polymerase chain reaction.
Results: (1) The levels of RXRalpha mRNA on placenta villi from the abortion group were significantly decreased as compared with those from normal group (0.