The theranostic nanoagent MoC for multi-modal imaging-guided cancer synergistic phototherapy.

Multifunctional theranostic platforms, especially single component-based platforms, enable both cancer treatment and real-time imaging as well as enhance the efficiency of treatment. In this study, 50 nm Mo2C nanospheres were explored as a "one-for-all" theranostic agent. The light-harvesting of Mo2C covered the entire near infrared region, and NIR irradiation concurrently triggered hyperthermia and reactive oxygen species (ROS) production; thus, synergistic outcomes of photothermal and photodynamic therapy could be realized.

SnWO as a theranostic platform for realizing multi-imaging-guided photothermal/photodynamic combination therapy.

Precise oncotherapy requires effective cancer treatments that are guided by clinical imaging techniques. One of the most representative cases is multi-imaging-guided phototherapy. This study presents a novel multifunctional theranostic agent of SnxWO3 tungsten bronze, which is an excellent light absorber in the near infrared (NIR) range.

MoS-Based multipurpose theranostic nanoplatform: realizing dual-imaging-guided combination phototherapy to eliminate solid tumor via a liquefaction necrosis process.

Theranostics that combines the disease diagnosis with treatment is of promising application in the foreground of personalized medicine to achieve a precise treatment with minimum side effects. In this work, we strategically designed a "four-in-one" theranostic nanoplatform for realizing the desired imaging-guided phototherapy, in which functions of fluorescent imaging, photoacoustic imaging tomography (PAT), photothermal therapy (PTT) and photodynamic therapy (PDT) were implemented by bioconjugated MoS nanosheets. The protagonist of MoS is a light-harvesting material in the near-infrared (NIR) region, which would produce localized hyperthermia at the tumor site to trigger the photothermal therapy effect for the tumor ablation as well as a PAT signal to depict the tumor concurrently upon NIR excitation.

Non-stoichiometric MoO quantum dots as a light-harvesting material for interfacial water evaporation.

We herein present oxygen-deficient molybdenum oxide quantum dots (MoO QDs), which possess matching-absorption-spectrum to solar light in both visible and near infrared regions, for proof-of-concept of interfacial water evaporation. Theoretical modeling suggests that the unique optical property of MoO QDs results from oxygen defect level, instead of localized surface plasmon resonance.