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Publications by authors named "Chuanjie Tian"

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LTBP2 inhibits prostate cancer progression and metastasis via the PI3K/AKT signaling pathway.
Xiaowen Zhang Chuanjie Tian Jianbin Cheng Weipu Mao Menglan Li

Exp Ther Med

September 2022

Biochemical recurrence (BCR) is a cause of concern in advanced prostate cancer (PCa). Thus, novel diagnostic biomarkers are required to improve clinical care. However, research on PCa immunotherapy is also scarce.

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lncRNA MNX1‑AS1 promotes prostate cancer progression through regulating miR‑2113/MDM2 axis.
Dong Liang Chuanjie Tian Xiaowen Zhang

Mol Med Rep

July 2022

A growing number of dysregulated long non‑coding (lnc)RNAs have been verified to serve an essential role in human prostate cancer. However, the underlying mechanisms of lncRNA MNX1 Antisense RNA 1 (MNX1‑AS1) in prostate cancer has not been explored. Therefore, the present study aimed to explore the function of MNX1‑AS1 in prostate cancer tumorigenesis and investigate the in‑depth mechanism.

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Synopsis of recent research by authors named "Chuanjie Tian"

  • - Chuanjie Tian's research primarily focuses on understanding the molecular mechanisms involved in prostate cancer progression and metastasis, particularly through the exploration of long non-coding RNAs (lncRNAs) and signaling pathways.
  • - One of Tian's significant findings indicates that LTBP2 plays a role in inhibiting the progression and metastasis of prostate cancer via the PI3K/AKT signaling pathway, highlighting its potential as a therapeutic target.
  • - Additionally, Tian's work on the lncRNA MNX1‑AS1 reveals its role in promoting prostate cancer tumorigenesis by regulating the miR‑2113/MDM2 axis, shedding light on the intricate regulatory networks involved in cancer progression.

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