Two new thymol derivatives from .

Two new thymol derivatives () were isolated from the aerial parts of . Their structures were elucidated on the basis of comprehensive spectroscopic data analysis as 8,9-dehydrothymol-3---glucoside (), and 9-(acetyloxy)thymol-3-yl (3-methylbut-2-enoate) (). All isolates were evaluated for cytotoxic activities with IC50 values greater than 50 μM against MCF-7, HeLa, A549, and Hep G-2 cancer cells.

Reversal of azole resistance in Candida albicans by oridonin.

Objectives: Candida albicans is a yeast that causes fungal infections with high mortality and is typically resistant to azole drugs. To overcome this resistance, we explored the combined use of oridonin (ORI) and three azole drugs, namely fluconazole (FLC), itraconazole (ITR) and voriconazole (VOR). Azole-resistant C.