Synopsis of recent research by authors named "Chuanhai Yang"
- Chuanhai Yang's recent research primarily focuses on the roles of long noncoding RNAs (lncRNAs) in neurobiology, particularly regarding myelination and cognitive function.
- One significant study demonstrates that the lncRNA TubAR interacts with tubulin proteins to facilitate microtubule assembly, which is crucial for oligodendrocyte maintenance and myelination in the cerebellum; its knockdown leads to severe neurological deficits in mouse models.
- In another pivotal work, Yang explores a novel intranasal nanoformulation combining melatonin, insulin, and THC as a potential therapeutic approach for Alzheimer's disease, showing promising results in reversing cognitive decline and alleviating neuropathologies in mouse models.